Oxazolidinone is a five-member heterocyclic ring exhibiting potential medicinal properties with preferential antibacterial activity. Scientists reported various synthetic procedures for this heterocyclic structure. Current review articles tried to cover each and every potential aspect of oxazolidinone like synthetic routes, pharmacological mechanism of action, medicinal properties, and current research activities.

Amaranthus, the fifth largest genus of the family Amaranthacea which covers around 60 species throughout world caught the attention of biological and biomedical researchers because of the presence of antiviral proteins specifically ribosomeinactivating proteins. These antiviral proteins exhibited N-glycosidase, DNAse, RNAse, immunomodulatory activities. Current article discuss the role of antiviral proteins present in family amaranthaceae. © 2011 IGJPS. All rights reserved.

Objectives: A review article on novel approaches on oral insulin delivery. Data Sources: Review articles on oral insulin delivery, Books. Study selection: This review consist of importance as well as current approaches for oral insulin delivery like liposomes, nanospheres, nanocubeics, erythrocytes, thiolated chitosan tablets, chitosan microspheres etc. Summary of content article: Type 1 diabetes mellitus is a metabolic disorder which arouse as a major health problem worldwide. Clinical management of insulin is done by insulin replacement therapy and current route of its administration is through subcutaneous injection having many challenges. To overcome the problems associated with insulin injections novel approaches for insulin administration are being explored. If insulin is administered orally, in the stomach rapid enzymatic degradation of insulin occurs and in the intestine insulin is digested and hence inactivated by the action of proteolytic enzymes occurs. This review consist of importance as well as current approaches for oral insulin delivery like liposomes, nanospheres , nanocubeics, erythrocytes, thiolated chitosan tablets, chitosan microspheresetc. This review also gives the information about current market status of oral insulin 5. Conclusion: The oral route is considered to be most acceptable and convenient route of administration for chronic therapy. Attempts have been made to achieve oral insulin delivery using various systems. Liposomes, microemulsions, nanocubicles, thiolated chitosan, chitosan microspheres and so forth have been prepared for the oral delivery of insulin.

Face recognition technology is a big area that consists of the many features in it but it also comes with some of the factors which affect this technology, one of the factors is Face aging which makes face recognition more difficult. As in India, a large number of children go missing every year. Also just using a photograph is not enough for the process to proceed smoothly and it results in a huge percentage of the missing child cases remain untraced. This paper presents a novel use of face recognition with face aging to overcome the limitation of existing systems. The proposed system has a portal where the public can upload an image of a suspected child and also have a feature where searching for any lost child is possible. The proposed system has mainly concentrated on an Age Conditional generative adversarial network (C-GAN) algorithm for face aging and the FaceNet algorithm for face feature extraction and face recognition.

Few analogues of 3-(3-fluoro-4-piperazine-1-phenyl)-1,3-oxazolidin-2-one were synthesized and structurally characterized using physical and spectral data. Current research work is to evaluate the potential of these analogues as antifungal agents. Two fungal strains, Aspergillus flavus & Penicillium chrysogenum were used in the Kirby bauer agar diffusion assay. Results revealed that 3-(3-fluoro-4-piperazine-1-phenyl)-1,3-oxazolidin-2-ones doesn’t have significant antifungal activity against P. chrysogenum but Ox 1.3 & Ox 1.5 have shown potential inhibition of A. flavus comparable to that of standard oxytetracycline. This antifungal activity can be attribute to the 4-acetylpiperazinyl ring in 3-(3-fluoro-4-piperazine-1-phenyl)-1,3-oxazolidin-2-one. Further tailoring up the structure can augment the drug discovery. © 2011 IGJPS. All rights reserved.