The present paper reports the occurrence of leaf roller, Sylepta derogata Fabricius (Lepidoptera : Pyralidae) on back mangrove, Hibiscus tiliaceus Linn. (family Malvaceae), exists in Bhitarkanika National Park, Rajnagar (Mangrove) Forest Division, Kendrapara, Odisha. Some biological observations and morphometric data on developmental stages of leaf roller has been studied and reported.

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Ayurveda, one of the ancient systems of medicine, holds a vast domain of traditional knowledge within himself. It is considered as the science of life and has been practiced in India since times immemorial. A very systematic and elaborate step-wise procedure known as 'Bhasmikarana' converts the metal from its zero valent state to a form with higher oxidation state, which is crucial from the point of view that during this process the toxic nature of the metal and its oxide is fully destroyed while rendering the metal oxide with high medicinal value. The mentioned Verse is in the text like Rasendra mangal, Rasarnava, Ras Ratna Samuchchaya, Ras Ratnakar, The verse signifies that the absorption &assimilation of different types of Bhasma of minerals / metals / sub metals & Sindoora kalpana for internal administration in human body. Reduction in the particle size is the motto of using in the form of Bhasma or Nano medicine. The finer the particle size of bhasma allows better rate of assimilation and absorption. This is a critical attempt to understand and apply the basis of Ayurvedic concept of Bhasma and the concept of Pharmacokinetics. Pharmacokinetics supports the studies of preclinical toxicology in animals (toxicokinetics) because the drug levels in plasma or tissues are often more predictive than the dose to extrapolate the toxicity data to man.

Ayurvedic system of medicine is the only one out of all traditional system of medicine where importance of metals for curing ailments was probably first recognized. Iron is the fourth common element and second most common metal in the earth crust and is a biologically essential component of every living organism. Despite the low requirement of iron in human body iron overload is rare and iron deficiency is common in certain parts of the world and in certain age groups6. Iron containing drugs used as hematinics are known to induce some adverse drug reactions -- gastrointestinal symptoms (nausea, vomiting, epigastric pain, colic pain, flatulence, constipation, black feces, and diarrhea. Iron containing compounds like Loha Bhasma, Kasis Bhasma and Mandura Bahsma are practiced since long and are indicated in a wide spectrum of dis-eases and can be a better alternative from Rasa shastra. Pharmacokinetics is proposed to study the absorp-tion, the distribution, the bio transformations and the elimination of drugs in man and animals. A primary aim of pharmacokinetics analyses is to determine bioavailability. Evaluation of Pharmaco kinetics of Loha bhasma, Kasis bhasma and Mandura bhasma were carried out. Serum iron was estimated using AAS. Pa-rameters like Cmax, Tmax etc. were calculated

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