INTRODUCTION:Maxillary implant overdenture has improved the quality of life for edentulous patients especially patients with atrophic maxilla. Sub-nasal lifting was introduced to solve the problem of severely atrophic anterior edentulous maxilla to allow insertion of dental implants. The type of attachment may influence the retention and stability of the prosthesis and thus, masticatory efficiency. Especially locator attachment is used with great success for improvement of implant-assisted over denture OBJECTIVES:To evaluate clinically and radiographically the effect of wearing implant-retained over denture in patients with atrophic anterior maxilla which was reconstructed by nasal lifting. Patient satisfaction was also evaluated. MATERIALS AND METHODS:This clinical trial was conducted on seven patients with edentulous atrophic anterior maxilla rehabilitated by Sub-Nasal Lifting, restored with bilateral two implants and grafted with Platelet-Rich Fibrin. For each patient an implant-retained over denture with locator attachments was constructed. Patient assessment was done using different three method including clinical, radiographic evaluation and patient satisfaction at three intervals: at time of over denture insertion, 3months and 6 months of denture use. RESULTS: All patients showed increased bone density around dental implants with slight decrease in marginal bone height, no mobility of each implant was detected .All patient showed increased well satisfaction throughout the follow up periods. CONCLUSIONS Two implant-assisted maxillary over denture is an acceptable treatment for patients with atrophic anterior maxilla and it showed increased patient satisfaction and favorable clinical and radiographic findings.