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(1974) de "Erkek E ğreltiotu", Erkek E ğreltiotu Tozu" ve "E ğreltiotu Ekstrakt ı" olmak üzere üç monograf yer almaktad ır.

Six saponins, cyclaminorin (1), deglucocyclamin (2), cyclacoumin (3), cyclamin (4), isocyclamin (5), and mirabilin (6) were isolated from the tubers of Cyclamen mirabile. Compound 6 is a new natural compound, and its structure was established as 3-[O-beta-[[beta-D-xylopyranosyl-(1-->2)]- [beta-D-glycopyranosyl-(1-->6)]-beta-D-glucopyranosyl-(1-->4)]-[be ta-D- glucopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl]-3 beta,16 alpha,28-trihydroxyolean-12-en-30-oic acid (6). The structure elucidation of this compound was accomplished using both spectral and chemical methods. Antimicrobial and uterocontractile activities of the saponins were also investigated.

From the tubers of Cyclamen coum (Primulaceae) three new saponins, cydaminorin (1), cyclacoumin (3) and mirabilin lactone (4) were isolated together with a known saponin, deglucocyclamin (2). The structures of the new compounds were established as 1 3/J,28-epoxy-3j1-(1 -2)1-a-i-arabinopyranosyI}-oxy}oIean-1 2-eno-30,28-lactone (4). Structure elucidations were accomplished using both spectral (NMR, MS, IR) and chemical methods.this study for the separation of the compounds. Sepralyte, and Silica gel 60 (70-23Omesh, Merck) were used as reversed-and normal-phases for chro-Planta Medica 63(1997)166-170 © Georg Thieme Verlag Stuttgart. New York matographic separations, respectively. Silica gel 60 F254 precoated Al sheets (0.2 mm, Merck) were used for TLC controls. Plantmaterial Cyclamen coum Miller was collected from central Anatolia, Yozgat, Saraykent, Turkey in September 1993 and February 1995. A voucher specimen (no. 95001) has been deposited in

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