A new tirucallane-type triterpenoid igniarine (1), and four known compounds meshimakobnol A (2), meshimakobnol B (3), ergosterol (4) and ergosterol peroxide (5), were purified from the methanol extracts of the fruiting bodies of Phellinus igniarius (DC. ex Fr.) Quél. The structure of 1 was elucidated using a combination of 1D and 2D NMR techniques and HR-ESI-MS analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumour cell lines and part of the tested compounds demonstrated weak cytotoxicity.
One new cytochalasin daldinin (1), 2 known cytochalasins 2 and 3, along with 2 steroids 4 and 5, were characterized from the methanol extracts of the fruiting bodies of Daldinia concentrica. The structure of new compound 1 was elucidated using a combination of 1-and 2-dimensional nuclear magnetic resonance spectroscopic and high-resolution electrospray ionization mass spectrometric analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumor cell lines and the tested compounds demonstrated moderate-to-weak cytotoxicity.
One new triterpenoid, hexagonin F (1) was characterized from the fruiting bodies of Hexagonia tenuis with the assistance of spectroscopic and spectrometric analytical methods. In addition, two triterpenoids and two steroids were also identified by comparison of their physical and spectroscopic data with those reported. The purified compounds were examined for their cytotoxicity against five tumor cell lines, however, only weak cytotoxicity was demonstrated.
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