Twenty-five compounds were identified from the essential oil of Globba pendula Roxb. by gas chromatography–mass spectrometry (GC-MS) with Selinene<d-> (22.09%) as the main component, followed by Ishwarane (6.52%). The essential oil was found to possess moderate NO inhibitory effect with IC50 of 41.68 ±4.51 µg/ml, significant cytotoxic activity against MCF7 and Hep3B cell lines with IC50 of 28.15±1.08 and 35.24±0.06 (µg/ml), respectively. This is the first report on volatile compounds and biological activities of essential oil of Globba pendula Roxb. collected at An Giang province, Vietnam.

Purpose: To assess the values of computed tomography in T staging of gingival cancer. Methods: A retrospective cross-sectional study conducted with 102 patients who had CT-scans and pathology results of carcinoma of gingiva at Ho Chi Minh City Oncology Hospital. This study evaluated the diagnostic value of CT in assessing the stage and bone invasion of gingival cancer by comparing CT assessment and pathology assessment. Results: There were 102 cases of gingival cancer in the study sample, of which 46 cases had tumor surgically removed. CT measurements of tumor size showed a strong correlation with macroscopic measurements with a Spearman correlation coefficient of 0.77. CT showed high diagnostic value in assessing bone and retromolar trigone invasion with sensitivity of 97.6% and 88.8%, specificity of 71.4% and 91.7%, positive predictive value of 95.2% and 80.0%, negative predictive value of 83.3% and 95.7%, respectively. In comparison between CTscans and histologic analysis in T staging, showed good agreement, with weighted kappa index of 0.6 (95% CI, 0.4-0.9). Conclusion: Computed tomography is a valuable method in T staging of gingival cancer. The CT assessment should evaluate factors according to 8 th AJCC to accurately evaluate the disease stage.