Elephantopus mollis and Elephantopus scaber were collected from Bay Nui region (An Giang province) for three years (2016)(2017)(2018)(2019). Their morphological characteristics, anatomical structures and medicinal powder were analyzed and compared with purpose of supplementing data to Elephantopus genus in Vietnam. The results showed that the morphological similarities of these two species occur at the sapling stage. At the mature stage, E. scaber has underground stem, purple flowers, and E. mollis has aerial stem, white flowers. In addition, these two species are able to be distinguished based on the size, thickness, tips shape or color of all leaves. The anatomical characteristics and the structure of the medicinal powder also showed differences in number and arrangement of xylem, and in covering trichomes of the two species at two stages (sapling and adult stages). Some byproducts such as calcium oxalate crystals, essential oil-secreting cells and inulin crystals were found in the vegetative organs of E. mollis and E. scaber collected from An Giang province.
Viêm loét dạ dày là bệnh đường tiêu hóa phổ biến và đã có nhiều nghiên cứu, phát đồ phòng trị bệnh này. Nhiều nghiên cứu được thực hiện cận lâm sàng và lâm sàng nhằm tìm ra các loại thuốc phòng trị nhưng mô hình động vật bị loét dạ dày vẫn chưa được thống nhất. Nghiên cứu này thực hiện khảo sát 3 mô hình loét dạ dày cấp tính trên chuột nhắt trắng Mus musculus bởi ethanol (60o, 70o và 80o), acetic acid (10%, 15% và 20%) và aspirin (350 mg/kg, 500 mg/kg và 650 mg/kg) với các chỉ tiêu đánh giá về tổng độ acid, chỉ số loét theo độ sâu, chiều dài và diện tích vết loét. Kết quả cho thấy cả 3 tác nhân gây loét đều có thể gây loét cấp dạ dày, trong đó, ethanol 70o, acetic acid 10% và aspirin 500 mg/kg là các tác nhân phù hợp để xây dựng mô hình gây loét dạ dày cấp tính.
Elephantopus mollis H.B.K. and Elephantopus scaber L. were collected atTo mountain in An Giang province and assessed for extraction efficiency, resistance ability to common bacterial strains in humans and animals, antioxidation, and toxicity. The extraction efficiency of two species was 11-26% and 16-28%, respectively and depending on the part of the plant. The flowers of both species had better antioxidant results than other parts with EC 50 at 32.2051 g/mL and 59.9778 g/mL, respectively, which was highly different from the rest of the plant (p<0.05). The leaves of both species had higher antibacterial properties than the other parts. For the six bacterial strains tested, both studied species had the strongest inhibiting ability for the growth of E. coli. (at a concentration of 200 mg/mL) different from that of Ampicillin (p<0.05). These two species were not toxic to Mus musculus at the dose of 8,000 mg/Kg.
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