Abstract Introduction: The prevalence of COVID-19 in Indonesia has increase especially in March to September 2020. One of the provinces affected by COVID-19 is Bali. This pandemic of COVID-19 makes the Bali’s local government publish various policies to reduce the prevalence of COVID-19. Traditional and religious leaders, youth leaders, political figures, and all elements of society in Bali has unite and more discipline to implementing the COVID-19 prevention protocol. To reduce the prevalence of COVID-19 in Bali, it is also needing to provide educate and give accurate information for the people of Bali. One of the solutions is to apply the concept of a family doctor, but as we see the pandemic situation, the whole society should apply physical distance for the prevention to COVID-19. Because of that, online health applications can be the effective solution to optimize health services, as the example is telemedicine. Discussion: The use of telemedicine is the one of solution for doctors and Bali’s people to reduce the prevalence of COVID-19 by maintaining distance and providing personal care services by online. The concept of this program is to create the educate applications and online consultations, and collaborating with Bali’s traditional villages to ask about the number of families that can access the internet, and for helping to optimize the distribution of services evenly. For the effective delivery of information about COVID-19 in Bali, the family doctor can collaborate with Bali’s traditional villages. Conclusion: According to research, family doctors play a very important role in the continuity of the patient's relationship with the doctor. By using telemedicine, we can do a prevention and educate people about the pandemic of COVID-19. Keywords: COVID-19, doctor family, Bali’s traditional village, telemedicine, online application

Background: Coronary heart diseases (CHD) is a disorder that caused by blockage of coronary arteries due to the process of atherosclerosis which disrupts the blood supply to the heart muscle. According to Sample Registration System (SRS) Indonesia in 2014, CHD is a second highest cause of death after stroke that is 12,9% of all cause of death in Indonesia. Therefore, this study aims to examining the effect of soybean extract encapsulated with Self Microemulsifying Drug Delivery System (SMEDDS) on LDL levels in coronary heart model rats. Based on various study, isoflavone aglycone genistein is the main flavonoid in soybean seed that has potential as an antioxidant. To increase bioavailability of aglycone isoflavones, a SMEDDS is needed. In this regard, the purpose of this reseach is to examine the potential of soybean seed (Glycine soja) extract to reduced cholesterol in CHD.Methods: The method used is a literature review with literature sources in the form of relevant articles from the search engines, namely Google Scholar, Pubmed, ScienceDirect, and Research Gate. Inclusion criteria included journals containing the keywords “soybean (Glycine soja)”, “Coronary Heart Disease”, “SMEDDS”, and “genistein isoflavone aglycone”.Result: Isoflavone aglycone as an potential antioxidant that is able to bind free radicals and and also lowering LDL, Triglycerides, and glucose levels in hyperglycemic states and increasing HDL.Conclusion : Soybean seed extract with SMEDDS encapsulation have a potential to decrease LDL level in coronary heart disease.