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Nyeri punggung bawah pada kehamilan digambarkan sebagai nyeri pada daerah lumbar, diatas sakrum yang menyebabkan ketidaknyamanan selama kehamilan. Akupresur titik bladder 23 merupakan metode non-farmakologi yang dapat mengurangi nyeri punggung bawah. Tujuan penelitian ini untuk mengetahui pengaruh akupresur titik bladder 23 terhadapintensitas nyeri punggung bawah ibu hamil trimester III di UPTD Puskesmas I Dinas Kesehatan Kecamatan Denpasar Utara. Penelitian ini menggunakan pre eksperimental dengan rancangan one grup pretest-posttest design.Sampel yang digunakan yaitu 12 orang ibu hamil trimester III dengan usia kehamilan 37-39 minggu dan di pilih secara purposive sampling. Data diambil dengan melakukan observasi intensitas nyeri punggung bawah sebelum dan sesudah dilakukan akupresur titik bladder 23. Responden melakukan akupresur sebanyak dua kali seminggu dengan durasi dua detik sebanyak 30 kali tekanan. Hasil intensitas nyeri punggung bawah sebelum perlakuan diperoleh nilai mean 4,17 dan setelah perlakuan berubah menjadi 2,67 dengan nilai ρ = 0,000 < α (0,05) dan nilai t (9,950). Simpulannya adalah ada pengaruh akupresur titik bladder 23 terhadap intensitas nyeri punggung bawah ibu hamil trimester III di UPTD Puskesmas I Dinas Kesehatan Kecamatan Denpasar Utara.Lower back pain in pregnancy described as pain in the lumbar region, above the sacrum which causes discomfort during pregnancy.Acupressurepoint bladder 23 is a non-pharmacological method that canreduce low back pain.This study aims to determine the effect of acupressure point bladder 23 on the low back pain level in third semester pregnant women in UPTD Puskesmas I of the Health Departement of North Denpasar. This is pre-experimental research with one group pretest-posttest design. The samples were 12pregnant women on third trimester with 37-39 weeks gestational age and were selected by purposive sampling. Data were collected byobserving the intensity of low back pain before and after treatment. Respondents did acupressure twice a week with the duration two seconds for each 30 times pressure. The results of low back pain intensity before treatment obtained a mean value of 4.17 and after the treatment there was reduce to 2.67 with a value of ρ = 0,000 <α (0.05) and t value (9,950). The conclusion is that there is an influence of acupressurepoint bladder 23 on the low back painintensityin third trimester pregnant women in UPTD Puskesmas I of the Health Departement of North Denpasar.

Background and objective: soybean tempeh contains isoflavones that are able to bind to estrogen receptors, so they have estrogenic properties. This study aims to prove that the administration of tempeh soybean extract during periods of perception can inhibit the formation of ovarian follicles. Method: posttest only control group design, using female rats aged 12-13 weeks with BB 150 g, a research site in Udayana University's integrated laboratory. Result: the results showed that there were significant differences in the mean number of follicles in the three groups, namely primordial, primary, secondary was p <0.01; atreticfollicles wasp <0.05. Conclusion: the administration of ethanol extract of tempeh during the perimenopause period can inhibit the formation of primordial follicles, primary follicles, and secondary follicles. High doses can increase the average number of atretic follicles.A large number of stimulated follicles grows and subsequently develops atresia, causing fewer primordial follicle reserves 9 . The process of apoptosis is controlled

The testis was composed by the cells of Leydig, Sertoli, and Spermatogenic. The cells formation itself was able to be disrupted by exposure to an endocrine disrupting chemical (EDC) since the prenatal period. The research was intended to prove that Genistein could obstruct the formation of Leydig cells, Sertoli cells, Spermatogenic of rats. The randomized post-test only control group design method was conducted towards white female Wistar rats, 12-13 weeks old, has been had one child, could normally eat and drink. The analysis unit was the child of mother rat treatment group that given Genistein of 10 mg/kg/day and the control group that received distilled water, each of them were 15. The research was done in the Laboratory of Faculty of Veterinary Medical, Udayana University, from January to July 2016. The computer was used for analyzing the data using, with α of 0.05. The result was the Genistein child had an average of 5.464 Sertoli cell, 11.120 Leydig cell, and 48.427 spermatogonia, whereas, the control group had an average of 8.173 Leydig cells, 12.987 Sertoli cells, and 69.547 spermatogonia. There were significant differences between the two groups (p 0.000). The conclusion was that an average of Leydig cells, Sertoli cells, and Spermatogonia lower in children whose their parent rats given Genistein during Periconception period.

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