Thrombosis related to central venous catheters is often underappreciated and misdiagnosed, despite its incidence and impact on patient morbidity and mortality. The purpose of this article is to offer a review of the literature, investigate the pathophysiology of the condition, and summarize the key points. Recommendations for the treatment and prevention of this complication are explored to help guide clinical practice.

Preventing infections related to central venous catheters requires the integration of clinical, organisational and workforce factors.