The cuneiforms are three wedge-shaped bones, forming the tarsus of the foot along with the talus, calcaneus, navicular, and cuboid. We present the case of a 70-year-old Caucasian woman with a left unique lateral cuneiform instead of second and third cuneiform bones. Additional cuneiform bones are rare anatomical variants which have been well described in the literature. Conversely, a lesser number of cuneiform bones have never been previously reported. To our knowledge, our article represents the first documented case of this anatomical variation.