Adult multiple xanthogranuloma (XG) is a rare late-onset variant of juvenile XG. It is characterized by the appearance of papules or nodules located preferably on the trunk. A case of a 54-year-old man with myelodysplastic syndrome is presented as a history of interest, who consulted due to the appearance of multiple brownish papules distributed mainly in the trunk. So far, there are only 22 cases of this clinical form reported in the literature, 9 of them associated with malignant hematological processes. We highlight the importance of this entity as a possible cutaneous marker of blood dyscrasias.

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about 80% within 2 years. 2 Radiotherapy, photodynamic therapy bleomycin, steroid, and 5-FU injections can be combined with surgery, but there are scarce information concerning specific techniques, doses, or success rate. [2][3][4] Many studies have reported successful treatment with laser therapy, whose best results are obtained, when using intense pulsed light or fractional lasers. However, when used in monotherapy, laser therapy shows recurrence rates similar to conventional surgery alone (45%-100%). 5 We present a new technique for recalcitrant auricular keloids, which combines surgery, contact cryotherapy, intralesional injections of 5-FU, and TA.

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