Apresentamos um exuberante caso de papilomatose reticulada e confluente de Gougerot-Carteaud em adolescente masculino previamente saudável, tratado com minociclina via oral 100 mg durante 30 dias, com clareamento expressivo das lesões e resposta sustentada após 6 meses de seguimento. A literatura recente relacionada com o tema é discutida.
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