Background:Loss of retention has been cited to be the most common cause of the failure of postretained restoration with irreversible consequences when materials with different compositions are in intimate contact at the post/adhesive interface. With this background, a study was conducted to improve the adhesion at the resin phase of fiber posts using silane and other chemical pretreatments.Materials and Methods:Hundred glass fiber-reinforced posts were tested with 4 different protocols (n = 25) using silane as a control (Group A) and other three experimental groups, namely, Group B-20% potassium permanganate, Group C-4% hydrofluoric acid, and Group D-10% hydrogen peroxide were pretreated on the postsurface followed by silanization. These specimens were bonded with dual-polymerizing resin-based luting agent, which were then loaded at the crosshead speed of 1 mm/min to record the shear bond strength at the post/adhesive interface. The data were analyzed using one-way ANOVA test for multiple group comparisons and the post hoc Bonferroni test for pairwise comparisons (P < 0.05).Results:Group B showed more influence on the shear bond strength when compared to other protocols, respectively (P < 0.001).Conclusion:Alone silanization as a surface treatment did not improve the bond strength. Combination of chemical presurface treatments followed by silanization significantly enhanced the bond strength at the post/adhesive interface.
The commercially available protein-digesting enzyme bromelain is derived from the pineapple fruit or stem. Bromelain from fruit and stems are produced in different ways and has varied enzyme compositions. "Bromelain" often refers to the "stem bromelain". Bromelain is a combination of several thiol endopeptidases and others including various protease inhibitors, glucosidase, cellulase, phosphatase, peroxidase, and escharase. Studies conducted in both the lab and on animals show that bromelain has a variety of fibrinolytic, anti-edematous, antithrombotic, and anti-inflammatory effects. The body can absorb bromelain to a significant extent without it ceasing its proteolytic activity or having any negative side effects. Numerous therapeutic advantages of bromelain include wound debridement, improved drug absorption, and the management of sinusitis, bronchitis, angina pectoris, surgical trauma, and thrombophlebitis. Additionally, it treats numerous cardiovascular conditions, diarrhoea, and osteoarthritis. Bromelain also encourages apoptotic cell death and exhibits some anti-cancerous properties. This review compiles the crucial traits, medical and dental uses of bromelain as well as its potential mechanism of action.
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