: Nowadays with increasing use of social media platforms for each and everything, there is an increasing trend for use of whatsapp based consultation for many diseases. But what’s app base impression has many limitations and may result in error in diagnosis. : To compare Whatsapp based visual impression versus actual impression in patients of common skin disorders. : In this cross-sectional comparative study held at Department of Dermatology of tertiary care hospital and referral centre in central India, 316 patients of common skin disorders attending Dermatology department were enrolled. Photographs of skin lesions in a patient suffering from skin disorders in pre-determined categories were taken and sent to by 2 independent expert dermatologists by Whatsapp and their impression was recorded. Later same patients were independently evaluated by same investigators by actual clinical examination. It was studied whether both evaluations were matched or not. : At the end of study overall, 69% patients’ photographic and clinical impression was matched. Among different groups of disorders, like fungal, bacterial, viral, pigmentary groups, average diagnosis matched in 51% to 80% cases. Highest percentage of diagnosis matched in pigmentary type of disorders at 80% and lowest percentage of diagnosis matched was 51% for papulosquamous disorders. : Whatsapp consultation is frequently sought by patients suffering from various dermatological problems but it’s not accurate and not 100 % reliable. So clinical evaluation always has an upper hand over an impression made over a photo.

Introduction: Minocycline because of its multiple advantages is considered as first-line therapy in the management of acne. However, conventional formulations of minocycline are associated with multiple side effects, thus limiting its use. Thus, extended-release formulation of minocycline was developed. Materials and Methods: This was an open-label, prospective, interventional, comparative, double-arm study. Patients with papulopustular acne were either received minocycline extended release (ER) 1 mg/kg/day or minocycline immediate release (IR) 100 mg/day for a period of 8 weeks. Safety was assessed by analyzing the adverse event (AE) profile in both the groups. Effectiveness was assessed by analyzing improvement in the mean inflammatory lesion count. Results: A total of 100 patients were included in the study, 50 in each group. A total of four AEs were reported by 2 (4.0%) patients in the ER group, whereas ten AEs were reported by 5 (10.0%) patients in the IR group. The mean inflammatory lesion count in the ER group at baseline was 14.95 ± 3.76, whereas in the IR group, it was 14.52 ± 3.38. Significant decrease in inflammatory lesion count was observed in both the groups during treatment period. Conclusion: The results of this study prove that ER formulation of minocycline is associated with better improvement in acne compared to IR formulation. The study also proves that ER formulation is associated with better safety profile compared to IR profile.