Cancer is one of the frequently talked and most feared diseases that have evolved, rather rapidly in the past two decades. Breast cancer, a multifactorial disease is the second most common malignancy related mortality among women worldwide. Routine diagnosis for breast cancer is usually done by mammography and histopathology, but current research data suggest that other non-disease specific biomarkers such as protein profiling, tumor specific hormones, hematocrit, serum proteins etc are also hypothesized to be associated with overall health outcome of the patients and can serve as a supplementary parameter to predict overall prognosis of the patients. The present study concerns about relative analysis of Hematocrit and WBC parameters among patients at the time of diagnosis along with the examination of ratio of Neutrophil-to-Lymphocyte (NLR), Platelet-to-Lymphocyte (PLR) and Lymphocyte-to-Monocyte (LMR) by fully automated clinical biochemistry analyzer and its correlation with other socio-demographic factors prevalent among the patients. For this purpose, preoperative blood samples of breast cancer patients were collected from Rajkot Cancer Hospital and results were compared with age and sex matched healthy volunteers. The present study conclude that high NLR ratio in 27%, high PLR ratio in 7.81 % and low LMR ratio in 14.75% of patients was obtained among the studied population.

Breast cancer is the second most common malignancy related mortality observed in women worldwide. It is multifactorial in nature having many factors including genetics, lifestyle factors, socioeconomical etc. playing role in variable occurance and heterogeneity towards treatment. Routine diagnosis for breast cancer is usually done by mammography and histopathology, but recent adavnces suggests the role of certain biomarkers such as tumour specic hormones, serum proteins, serum enzymes etc as a supplementary parameters to predict overall prognosis of the patients. In the present study, relative analysis of the levels of ALP (alkaline phosphatase), LDH (lactate dehydrogenase) and Lipase enzyme is determined among breast cancer patients at the time of diagnosis using semi automated clinical biochemistry analyzer. further correlation is done with other socio-demographic factors prevalent among the patients. For this purpose, preoperative blood samples of breast cancer patients were collected from Rajkot Cancer Hospital and study concludes that higher expression of LDH was found in 50% of breast cancer patients, while 31.81% of breast cancer patients had higher expression levels of lipase and ALP enzyme among the study population.