Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year >2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis. In addition, neurological complications in children were assessed due to their atypical clinical features. Finally, dengue infection and Japanese encephalitis were compared for pathogenesis and main clinical manifestations.

Exposure to the Great Famine in early life had sex-specific association with moderate-severe NAFLD. This indicates that malnutrition in early life may influence the development of adult NAFLD; thus pregnant women and their infants and children may require the highest priority in obtaining nutritional relief.

Lectins are a group of proteins with carbohydrate recognition activity. Lectins are categorized into many families based on their different cellular locations as well as their specificities for a variety of carbohydrate structures due to the features of their carbohydrate recognition domain (CRD) modules. Many studies have indicated that the direct recognition of particular oligosaccharides on viral components by lectins is important for interactions between hosts and viruses. Herein, we aim to globally review the roles of this recognition by animal lectins in antiviral immune responses and viral pathogenesis. The different classes of mammalian lectins can either recognize carbohydrates to activate host immunity for viral elimination or can exploit those carbohydrates as susceptibility factors to facilitate viral entry, replication or assembly. Additionally, some arthropod C-type lectins were recently identified as key susceptibility factors that directly interact with multiple viruses and then facilitate infection. Summarization of the pleiotropic roles of direct viral recognition by animal lectins will benefit our understanding of host-virus interactions and could provide insight into the role of lectins in antiviral drug and vaccine development.

Taking advantage of multiple new remote sensing data sources, especially from Chinese satellites, the CropWatch system has expanded the scope of its international analyses through the development of new indicators and an upgraded operational methodology. The approach adopts a hierarchical system covering four spatial levels of detail: global, regional, national (thirty-one key countries including China) and "sub-countries" (for the nine largest countries). The thirty-one countries encompass more that 80% of both production and exports of maize, rice, soybean and wheat. The methodology resorts to climatic and remote sensing indicators at different scales. The global patterns of crop environmental growing conditions are first analyzed with indicators for rainfall, temperature, photosynthetically active radiation (PAR) as well as potential biomass. At the regional scale, the indicators pay more attention to crops and include Vegetation Health Index (VHI), Vegetation Condition Index (VCI), Cropped Arable Land Fraction (CALF) as well as Cropping Intensity (CI). Together, they characterize crop situation, farming intensity and stress. CropWatch carries out detailed crop condition analyses at the national scale with a comprehensive array of variables and indicators. The Normalized Difference Vegetation Index (NDVI), cropped areas and crop conditions are integrated to derive food production estimates. For the nine OPEN ACCESSRemote Sens. 2015, 7 3908 largest countries, CropWatch zooms into the sub-national units to acquire detailed information on crop condition and production by including new indicators (e.g., Crop type proportion). Based on trend analysis, CropWatch also issues crop production supply outlooks, covering both long-term variations and short-term dynamic changes in key food exporters and importers. The hierarchical approach adopted by CropWatch is the basis of the analyses of climatic and crop conditions assessments published in the quarterly "CropWatch bulletin" which provides accurate and timely information essential to food producers, traders and consumers.