The Fazekas scale [1] is a widely used method to visually rate hyperintense white matter signal abnormalities (WMSA) in magnetic resonance imaging (MRI) data, both in clinical practice and research [1-4]. High Fazekas WMSA burden (i.e. confluent WMSA, Fazekas 2 or 3 scores) is associated with greater cognitive www.aging-us.com
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