Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles as Biologically Active Heterocycles.-Some of the new compounds such as (VIa), (VIIIc), and (IXb) display antimicrobial and antitubercular activity.-(KAGTHARA, PREETI R.; SHAH, NIRAJ S.; DOSHI, RAJEEV K.; PAREKH, H. H.; Indian J.

A number of new arylamides (2a-o), sulphonamides (3a-p) and 5-oxo imidazolines (4a-o) have been synthesised by the condensation of acid hydrazide of o-benzoylene-2,1-benzimidazole 1 with different aromatic acid chlorides, aryl carboxy sulphonylchlorides and azlactones in dry pyridine. All the productswere evaluated invitro for their antimicrobial activity against several microbes and antitubercular activity against Mycobacterium tuberculosis H37Rv.

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