Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis.

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This meta-analysis was conducted to evaluate the effects of microdebrider-assisted inferior turbinoplasty (MAIT) versus other techniques in treating inferior turbinate hypertrophy. The protocol was registered in PROSPERO (CRD 42019126157). Cochrane Register of Controlled Trials CENTRAL, which includes MEDLINE, was searched from inception until December 2021. One hundred twenty-four records were retrieved from the search of the electronic database and other sources. Thirteen articles were selected and analysed quantitatively. There was a significant reduction of nasal obstruction in microdebrider compared to radiofrequency by visual analogue scale, but not by objective evaluations. Microdebrider has similar effect in reducing nasal obstruction to submucosal resection and laser. There was a higher incidence of postoperative bleeding with a microdebrider compared to radiofrequency, but shorter operative time and less intraoperative blood loss compared to submucosal resection. In conclusion, the effect of MAIT is comparable to submucosal resection, laser and radiofrequency in reducing nasal obstruction. While microdebrider has a shorter operative time and less intraoperative blood loss than submucosal resection, postoperative bleeding is greater than with radiofrequency.

In contrary to the infantile hemangioma, adult hemangioma differs in terms of its rarity, gender prevalence, location and presenting symptoms. We report a case of a 61-year-old gentleman with right vocal cord cavernous hemangioma who presented to us with the complaint of hoarseness for 6 months duration. Endoscopic laryngeal microsurgery and excision biopsy was performed and the mass was completely excised. Post operatively, the voice improved with no evidence of recurrence.International Journal of Human and Health Sciences Vol. 04 No. 01 January’20 Page : 67-69