Traditional medicine has a lot to give towards the world’s health, especially now that limits to conventional pharmacology has occurred. New scientific methodologies may spark a rebirth in global health research and development if rich and developing countries pooled their research capacities with inequitable collaborations. The Cassytha Filiformis has many medicinal uses. It is a parasite plant that has been used for medicinal purposes and other ornamental purposes in many parts of the world, and has found employment in Siddha, European, Ayurveda and Chinese folk medicine. In this review, the ethnobotany, phytochemistry and pharmacological benefits of Cassytha filiformis are discussed.