Squamous cell carcinoma in children and adolescents is extremely rare. Less than 80 case reports have been reported in the literature since it was first reported in 1868. In this article, we intend to report a case where a 16-year-old girl who presented with complaints of change in voice was found to have early-stage vocal cord carcinoma on evaluation.

Cancer is a leading cause of death worldwide. There are a lot of cancer causing agents which are divided as physical carcinogens, chemical carcinogens and biological carcinogens. But most of the carcinogens or causes of cancer are related to our lifestyle like diet, habit, occupation, radiation and some infection, etc. Chemoprevention is highly necessary to prevent cancer related preterm death. For this besides avoiding the causes of cancer we should concentrate ourselves on our diet. Because, numerous phytochemicals derived from edible plants have been reported to interfere with a specific stage of the carcinogenic process. Many mechanisms have been shown to account for the anticarcinogenic actions of dietary constituents and recently attention has been focused on intracellular-signalling cascades as common molecular targets for various chemopreventive phytochemicals. In this study, we tried to describe lifestyle related causes of cancer and the molecular basis of cancer prevention through the phytochemicals.

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Three 0.15% carbon steel samples containing small additions of vanadium and nitrogen singly or in combination have been carburized in a natural Titas gas atmosphere at a temperature of 9500C and a pressure of about 15 psia for time periods ranging from 1 to 5 hours and quenched in 10% brine from the carburizing temperature of 9500C after pre-cooling to 8600C in the furnace followed by tempering at a low temperature of 1600C. The structure and properties of the carburized and heat treated specimens were studied systematically by optical microscopy, surface hardness and microhardness measurements, X-ray diffractometry and impact tests. It was found that vanadium without nitrogen does not have any effect in the formation of retained austenite while vanadium with nitrogen is effective in promoting the formation of retained austenite in the case of carburized and hardened steels. It was also found that vanadium alone and vanadium with nitrogen refine the martensite platelets (needles) in the case of carburized and hardened steels, vanadium with nitrogen being more effective. Microhardness measurements have shown that vanadium improves the case hardness and the core hardness values; vanadium with nitrogen is more effective than vanadium alone in increasing the case hardness and the core hardness. The hardenability is found to increase with the increase of austenite grain size and with the extent of carbon penetration of the case of carburized steels. Vanadium as vanadium carbide, VC are detrimental to toughness and vanadium as vanadium carbonitride, V(C, N) are beneficial to toughness of the core of low carbon steels in carburized and hardened condition.

Sustainable health care gets paramount importance when cost benefits risk of main stream medical system has created enormous challenge for common masses. It becomes too evident when people living in slums, tribal areas and remote village don't have access to basic health care. Alternative systems especially Unani system which has huge base of natural drug products and is a culture friendly system serves an important filling gap in this scenario. More over the limitations of the present system has compelled the civilized societies to turn to this natural system which synchronizes well with the evolutionary adoptive measures of human race. The paper emphasizes the challenges and enumerates the potential of Unani system to fetch up a self fulfilling sustainable health care.