The ranking of Critical Success Factors (CSF) of Healthcare Management Information System (HMIS) help practitioners to identify vital factors from the trivial many that are essential for its success. The objective of this study is to rank the CSF of HMIS using a suitable Multi-Criteria Decision Making technique (MCDM). Here, Analytic Hierarchy Process (AHP) is the MCDM used to determine the relative importance of the CSF in influencing the adoption and use of HMIS. In order to rank the factors, this study is planned and performed in two stages. At the first stage to identify the critical success factors of HMIS, a through literature review is made. At the second stage, a pair wise comparison is designed based on AHP method to collect the opinions of experts and distributed among 15 persons of the organizational experts/academicians. The pairwise comparisons got from this stage are analysed by AHP. The research findings indicate that the critical success factors in HIS have different priorities and weights.The weightage got from AHP can also be used for ranking of various HMIS installations in different hospitals.