We experimentally demonstrate a high-fidelity entanglement swapping and a generation of the Greenberger-Horne-Zeilinger (GHZ) state using polarization-entangled photon pairs at telecommunication wavelength produced by spontaneous parametric down conversion with continuous-wave pump light. While spatially separated sources asynchronously emit photon pairs, the time-resolved photon detection guarantees the temporal indistinguishability of photons without active timing synchronizations of pump lasers and/or adjustment of optical paths. In the experiment, photons are sufficiently narrowed by fiber-based Bragg gratings with the central wavelengths of 1541 nm & 1580 nm, and detected by superconducting nanowire single-photon detectors with low timing jitters. The observed fidelities of the final states for entanglement swapping and the generated three-qubit state were 0.84 ± 0.04 and 0.70 ± 0.05, respectively.

Endophthalmitis following globe perforation with a hypodermic needle EDITOR,-Exogenous endophthalmitis is a common complication of intraocular foreign bodies (IOFBs). 1 It commonly occurs in association with a non-metallic foreign body and often results in profound visual loss. 2 Early diagnosis and treatment with intravitreal antibiotics are essential in its treatment. 3 We describe an unusual case of exogenous endophthalmitis caused by a heroin filled needle, the patient rapidly losing vision despite active intervention. CASE REPORTA 24 year old remand prisoner presented to the casualty department with a vague 2 day history of visual loss in his right eye. He had been stabbed in the eye 2 days previously with a hypodermic needle, which had recently been used for heroin injections.The patient had a visual acuity of hand movement vision in the aVected eye, which was inflamed and had a fibrinoid uveitis. A 3 mm hypopyon was present but a puncture wound was not visible. No fundus view was present. A high reflectivity shadow was seen in the vitreous on B scan ultrasonography ( Fig 1A) and an intraocular hypodermic needle was confirmed on plain x ray ( Fig 1B).The patient underwent a vitreous biopsy and intravitreal ceftazidine 2 mg/0.1 ml, vancomycin 2 mg/ml, and amphotericin B 0.005 mg/ml. The following day, a three port pars plana vitrectomy was performed. Postoperatively, the retina was observed to be detached with two giant retinal tears, one temporally and one nasally. Widespread periphlebitis and retinal necrosis was noted (Fig 2). The broken hypodermic needle was recovered and removed through a corneal incision. Retinal detachment repair was undertaken with heavy liquids, silicone oil, and endolaser photocoagulation. Postoperatively, he was treated with intravenous ciprofloxacin 750 mg twice daily, chloramphenicol eyedrops 1 ⁄2 hourly, atropine eyedrops 1% twice daily, Pred Forte eyedrops (Allergan) 1 ⁄2 hourly, and 40 mg prednisolone orally.The endophthalmitis settled slowly postoperatively, the retina remained flat but vision was reduced to perception of light. The vitreous biopsy grew Streptococcus oralis which was sensitive to chloramphenicol. COMMENTPenetrating eye injuries predominantly occur in young males, and are a common cause of monocular visual loss. 4 5 Endophthalmitis occurs in around 15% of patients with intraocular foreign bodies, the commonest organisms being Staphylococcus epidermidis (23.4%) and mixed organisms (17.3%). The visual prognosis is particularly poor with concurrent infection, 82.3% of patients having no perception of light.The timing of surgery remains contentious. Many authors recommend vitrectomy within 14 days of presentation, particularly if there is retinal detachment. The advantage of intervening before proliferative vitreoretinopathy has develops usually outweighs the universal risk of intraoperative haemorrhage in a recently traumatised globe. In our case endophthalmitis and sight loss developed as a result of Streptococcus oralis contaminated hypodermic needle, whic...

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The Ocean Color and Temperature Scanner (OCTS) for NASDA's Advanced Earth Observing Satellite (ADEOS), currently being developed by NEC under contract with NASDA, is a satellite-borne optical remote sensing sensor for the simultaneous measurement of ocean color and sea-surface temperature.The OCTS will scan a swath of the earth 1400km wide from sun-synchronous orbit at 800km altitude, using a rotating mirror.It will produce 3Mbps image data, covering the visible to thermal infrared spectral range, in 12 bands, simultaneously transmitted to the earth station. This paper provides description of OCTS performance, and system design concept.

BackgroundThe purpose of this study was to evaluate the safety and efficacy of a long-term, twice-daily brinzolamide 1%/timolol 0.5% fixed combination ophthalmic suspension (BRINZ/TIM-FC) in Japanese patients with open-angle glaucoma (primary open-angle, normal-tension, exfoliation, or pigmentary) or ocular hypertension.MethodsThis was a prospective, nonrandomized, multicenter, open-label, Phase III study of Japanese patients aged ≥20 years with diagnoses of open-angle glaucoma or ocular hypertension. Patients were treated with topical BRINZ/TIM-FC twice daily for 52 weeks. The primary endpoint was mean reduction from baseline in intraocular pressure. Data were analyzed using repeated-measures analysis of variance and t-tests. Adverse events and ophthalmic, physiologic, and laboratory parameters were measured throughout the study as safety endpoints. A total of 126 patients (mean ± SD age, 63±12 years) were enrolled, and 125 received BRINZ/TIM-FC.ResultsMean intraocular pressure was significantly reduced from baseline at weeks 4 through 52, with changes ranging from −4.1 mmHg to −5.7 mmHg (P<0.0001, all time points). Adverse events related to BRINZ/TIM-FC treatment were observed in 22% of patients. No substantial changes from baseline were observed in ophthalmic, physiologic, or laboratory variables.ConclusionLong-term, twice-daily BRINZ/TIM-FC therapy produced and maintained significant intraocular pressure reductions and was generally well tolerated in Japanese patients with open-angle glaucoma or ocular hypertension.