Introduction:Sarcoma is a rare entity with the primary pancreatic sarcoma represents a diagnostic challenge. Material and Methods: I reviewed articles particularly radiology studies in English language found in PubMed that were published recently to draw conclusions. Results: The common presenting symptom is vague abdominal pain. The described imaging appearance of such entity which shared between the different subtypes is a large heterogenous solid mass with frequent cystic degeneration/necrosis. The regional lymph nodes are rarely involved. Overall, poor prognosis of primary pancreatic sarcoma was reported. Conclusions: Although primary pancreatic sarcoma diagnosis remains a challenge, imaging differentiation from pancreatic ductal adenocarcinoma may be possible.
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