Research has been conducted to investigate the influence of the Science Technology Society (STS) learning model which is assisted by social media Facebook (FB) in science learning. This research was conducted in a group of junior high school students in Tondano, North Sulawesi, Indonesia. The research method is a Quasi-Experiment Posttest-Only Control Group Design. The experimental group was treated with the STS learning model assisted by FB, and the control group with lectures, discussions, question, and answer. The number of samples in the experimental group consisted of 25 students and the number of samples in the control group was 25 students. The results of the statistical analysis concluded that there was an influence of the STS learning model with the help of Facebook social media on improving student learning outcomes in science learning in junior high school students. The research data showed that the average post-test score of student learning outcomes in the experimental group was 88.5 higher than in the control group score was only 68.9. The implication of the research results is that the use of Facebook social media in the learning process will make teachers and students interact not only in the classroom. In addition, the STS learning model arouses students’ interest in science learning, especially related to strengthening scientific literacy