Background: Tracheostomy is an alternative that is widely used as airway access after the use of a ventilator in the care of critically ill patients. Several factors are known to influence the outcome in patients undergoing tracheostomy. This study aimed to compare the outcomes of critically ill patients installed with mechanical ventilation performed early and late tracheostomy in Dr. M Djamil General Hospital, Padang, Indonesia. Methods: This study was an analytical observational study with a cross-sectional approach. A total of 97 research subjects participated in this study. Data analysis was carried out with the help of SPSS software in a univariate and bivariate manner between tracheostomy time (early and late) with patient outcomes in the form of death and length of stay. Results: There was a statistical difference in the mortality rate in critically ill patients with mechanical ventilation performed early and late tracheostomy, p = 0.014. There is a statistical difference in the length of stay in the intensive care unit in critically ill patients with mechanical ventilation performed early and late tracheostomy with p = 0.000. Conclusion: There are differences in outcomes in the form of mortality and length of stay in critically ill patients who have tracheostomy installed at Dr. M. Djamil General Hospital Padang, Indonesia.

Breast cancer is a condition of uncontrolled breast cell proliferation that most frequently develops from the ductal epithelial cells (85%) or lobules (15%) of the breast glands. Poor prognoses for patients can result from cancer's extensive organ metastasis, now the second largest cause of cancer death in women. This study aims to identify the variables that affect how well patients with the operable breast cancer subtype Luminal B respond to treatment at RSUP DR M Djamil Padang. This research used a cross-sectional methodology with a retrospective study approach to identify characteristics that affect the treatment outcome for operable breast cancer subtype luminal B at RSUP DR. M. Djamil Padang. From August to November 2022, the study was carried out in the Oncology Surgery Division of RSUP DR. M. Djamil Padang. With HER2 being the main component, multivariate analysis revealed that HER2 and the kind of therapy were significantly connected with the treatment outcome for cancer patients.