Hereditary Multiple Exostosis is a rare bone disease in pediatric age group. It is an autosomal dominant disorder, characterized by excessive bony overgrowth arising from lateral aspect of metaphysis of long bone, covered by a cartilaginous cap. These lesions remain asymptomatic clinically. When symptomatic, a variety of health hazards can arise like chronic pain, skeletal deformity, neuro-vascular compression etc. Malignant transformation is a rare, but feared complication. Diagnosis can be made by simple radiographic examination, when symptoms arise. Treatment is only conservative or surgical. SARS- CoV-2 may infect children with any pre-existing disease, like HME in the same proportion of healthy children. We report a rare case of hereditary multiple exostosis, simultaneously suffering from covid-19 disease, that has not been reported previously.

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