Demam berdarah (DB) / dengue fever (DF) adalah penyakit yang ditularkan melalui gigitan nyamuk, terutama Aedes aegypty atau Aedes albopictus sebagai vektor dari virus dengue. Penyebab dari DF adalah infeksi dari salah satu virus dari 4 serotipe virus dengue (DENV-1, 2, 3, dan 4). Pengendalian vektor virus dengue dapat dilakukan dengan gerakan pemberantasan sarang nyamuk (PSN) 3M plus. Tujuan kegiatan pengabdian masyarakat pada kelompok PKK RT. 6 RW.28 Bukit Mutiara Jaya III adalah untuk meningkatkan ketentraman masyarakat melalui peningkatan kesehatan dan penerapan aplikasi BUTIK untuk mempermudah PSN dan mempercepat proses pelaporan. Metode pelaksanaan pengabdian masyarakat dilakukan dengan survey lokasi, mengurus permohonan menjadi mitra dan ijin kegiatan kepada ketua PKK. Pelaksaan pengabdian kepada masyarakat meliputi sosialisasi penggunaan aplikasi BUTIK, anggota PKK memasang aplikasi pada smartphone milik pribadi, kemudian pelaksanaan PSN ke rumah warga dengan menggunakan aplikasi BUTIK. Hasil kegiatan berdasarkan kuisioner menjunjukkan 97% peserta setuju bahwa aplikasi BUTIK membantu dan bermanfaat dalam pelaksanaan PSN. Kesimpulan dari kegiatan pengabdian masyarakat yang telah dilakukan adalah Aplikasi BUTIK telah disosialisasikan dan diterapkan kepada kelompok PKK Rt. 6 Bukit Mutiara Jaya III dan peserta merasa aplikasi BUTIK bermanfaat untuk peningkatan kesehatan dan mempermudah pelaporan PSN di kelompok PKK Rt. 6 Bukit Mutiara Jaya III.
Antibiotics from the aminoglycoside group, such as gentamicin, are frequently used for the infection therapy of gram-negative bacteria including Salmonella typhi. Some studies show that gentamicin can cause hepatotoxicity and increase the level of SGPT (serum glutamic pyruvic transaminase). The purpose of this research is to figure out the decreasing SGPT level of male Wistar rats induced by gentamicin with the purslane ethanol extract. This research employed a post-test only control group design, utilizing 25 male Wistar rats divided into 5 groups. The normal control group (NorG) was without any treatment, while the positive control (PG) was intraperitoneally injected with gentamicin 60 mg/kg of rat body weight. The treatment groups consisted of P1, P2, and P3 were intraperitoneally injected with gentamicin at the dosage of 60 mg/kg of rat body weight for 7 days and then administered with purslane ethanol extract respectively at the dosage of 200, 300, and 400 mg/kg of rat body weight per oral for 7 days. The analysis on the SGPT level was conducted with the IFCC modification method using chemistry analyzer. One way ANOVA test shows that there were significant differences in SGPT levels among groups. LSD post hoc test shows that purslane ethanol extract at the dosage of 400 mg/kg of rat body weight significantly decreased the SGPT level (p<0.05) when compared to the positive control group. The administration of common purslane ethanol extract at the dosage of 200, 300, and 400 mg/kg of rat body weight can decrease the SGPT level of male Wistar rats induced by gentamicin.
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