Cymbopogon citratus (C. citratus) has antioxidant, anti-inflammatory, and chemoprotective properties. This study was conducted to evaluate the protective effect of C. citratus aqueous extract against hydrogen peroxide (H2O2)-induced oxidative stress and injury in the reproductive system of male rats. The twenty-five rats used in this study were divided into five groups, comprised of five rats each. The control group received standard food and drink. The H2O2 group received standard food and water with 0.5% H2O2. The rats in the H2O2 + C. citratus group and H2O2 + vitamin E group received standard food, H2O2, and C. citratus [100 mg·kg(-1) body weight (bw)], or vitamin E as an antioxidant reference (500 mg·kg(-1) bw), respectively. The C. citratus group was given C. citratus (100 mg·kg(-1) bw) in addition to the standard food and drink. The treatments were administered for 30 days. The H2O2 treatment significantly (P < 0.05) decreased body, testicular, and epididymal weight, as well as glutathione (GSH) level, but markedly increased malonaldehyde (MDA) in serum and testes homogenates. The rats treated with H2O2 exhibited testicular degeneration and significant reduction in sperm viability, motility, count, and rate of normal sperm. The C. citratus, vitamin E, and H2O2 treatment significantly (P < 0.05) increased the body, testicular, and epididymal weight, testosterone level, the values of the various sperm characteristics, and GSH. However, this treatment markedly reduced MDA in serum and testes homogenates, as well as testicular histopathological alterations in the H2O2-treated rats. The C. citratus aqueous extract reduced oxidative stress and protected male rats against H2O2-induced reproductive system injury.
The aim study to search the role of selenium in Biochemical parameters of role of selenium in reducing the side effect codeine in the level of certain hormones The study included 30 female domestic rabbits were divided into six groups of 5 animals per group show by studying the presence of high-rise moral (P ≤0.01) in the rate of the hormone AMH levels in serum in the third-sixth group compared to the first group. Absence of significant difference in the rate of the hormone AMH levels in the second group and the fourth-fifth group compared to the first group and the occurrence of high-low morale (P≤0.01) in rate progesterone levels in the blood serum in Group second and Group third and Group fourth fifth and sixth group and the group compared to the first group. And the presence of high moral decline (P≤0.01) in the rate of estrogen levels in the blood serum in Group second and Group third and Group fourth and fifth and sixth group and the group compared to the first group. And the occurrence of highly significant in the rate of LH hormone levels drop in blood serum in Group fourth compared to the first group. and the absence of significant differences in the rate of LH hormone levels in the blood serum in the first group and the fifth group and the third and sixth group compared to the first group. And a decline highly significant at the level of probability (P≤0.01) in the rate of FSH levels in serum in third Group and fifth Group and sixth group compared to the first group. The results showed no significant differences in the rate of FSH levels in serum in the scond group compared to the first group.
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