We analysed the effect of prostoglandins analogues application on the course of postoperative period of cataract phakoemulsification in 58patients with primary open-angle glaucoma. All patients before the operation had normal intraocular pressure (on average 15.6±0.07mm Hg), the optical coherent tomography showed normal parameters of retina thickness in 1mm zone and the macula volume in 6mm zone. Instillation of nonsteroid anti-inflammatory drug after the operation lasted 6–8weeks, and prostoglandins analogues continued to be instillated during all period of observation. The course of the early postoperative period was areactive. Average visual acuity on the first day was 0.69±0.05, in 6–8 weeks – 0.85±0.05. The average level of intaocular pressure during application of prostoglandins analogues on first day was 16.9±0.37mm Hg, and in 6–8weeks – 15.1±0.28mm Hg. Optical coherence tomography revealed little change of retina thickness and macular area volume before the operation and in 6–8weeks after it was regarded as an error of measurement method.Thus, continuation of instillations of prostoglandins analogues in pre- and postoperative period in uncomplicated phakoemulsification in patients with primary open-angle glaucoma promote continuity in treatment, support com-plience and provide stable intraocular pressure without the expressed reactive hypertensia. Application of nonsteroid anti-inflammatory drug during 6–8 weeks after phakoemulsification in patients with primary open-angle glaucoma serves as an effective measure of prevention of inflammation of an anterior and posterior eye segment during pros-toglandins analogues treatrment.

Authors analyze efficiency of application antiseptics of a miramistin in prevention of infectious complications in case of repeated intravitreal injections of VEGF inhibitor Ranibizumab in 156 patients with the age related macular de-generation. 0,01% solution of antiseptic Miramistin (Okomistin®) was instillated 4 times per day two days before operation to all patients for the purpose of infection prevention. Just before the operation (60 and 30 minutes before) and right after it instillations of antiseptic continued within a week after intravitreal injection. During the operation in the conditions of the operating room with keeping of all rules of aseptic, three minutes prior to operation the surgery field and the conjunctival cavity of the patient were twice processed by 5% povidone-iodine solution (Betadine). The results analysis showed no expressed signs of irritation of the eyes connected to miramistin treatment preceding the operation. In the postoperative period all patients endured antiseptics well. Within a week of applications there were no complaints about pain, burning, foreign body sensation or hazy vision after the medicine instillation, and biomicroscopic research revealed no signs of inflammatory injection of conjunctiva or sclera, no cornea epitheliopathy, there was no cellular response in moisture of the anterior chamber and vitreous body. Thus, the authors state that antiseptics Okomistin® as an additional measure of prevention of infectious complications in case of intravitreal injection provide high level antimicrobic protection with no risk of development of microbial resistance.