Background and Aim: Present study provides with more anatomical information on the structure and form of the bones forming the cranium of the Nile crocodile helps in understanding the interpretation of X ray images and surgical affection of the crocodile heads. Materials and Methods: The present study was conducted on six heads of the Nile crocodile (Crocodylus niloticus). The heads were removed from their bodies and prepared by hot water maceration technique. The bones of the skull were studied separately and identified by using a specific acrylic color for each bone. Results: The cranium of the crocodile composed of the cranial bones and the facial bones. The crocodile had four paired paranasal sinuses; the antorbital, the vomerine bullar, the pterygopalatine bullar and the pterygoid sinuses. The mandible of crocodile formed from six fused bones (articular, angular, suprangular, coronoid, splenial and dentary). The X ray images were applied for identifying the paranasal sinuses which their contribution to the morphological organization of the head. Conclusion: this results show a bony variation between the crocodile, mammals and also the birds that paves the way to the comparative anatomical and radiological studies.
The present study provides detailed anatomical description of the parotid and mandibular salivary glands of the one humped camel with their segmentation based on arterial blood supply and salivary ducts; to facilitate partial removal of the pathologic gland. The shape, position, relations and blood supply of both salivary glands with their ducts were studied on six cadaveric heads. The mandibular and parotid ducts were injected with Urographin® as contrast medium; through inserting the catheter into their openings in the oral cavity; then applying lateral radiography immediately after the injection. The common carotid arteries were injected with red Latex Neoprene and dissected. The parotid gland was irregular rectangular and had five processes while the mandibular gland was irregular triangular with rounded proximal and pointed distal extremity. The parotid duct enters the oral cavity on the cheek opposite the upper 4th molar tooth. The mandibular duct opens in the oral cavity at the sublingual caruncles on the sublingual floor, just about 2cm cranial to frenulum linguae. Both The parotid and the mandibular salivary glands could be divided into four segments. Partial removal of the pathologic parotid or mandibular salivary glands could be performed based on their segmentation. Tumor arrest could be established by ligation of the arterial supply of specific part of the gland.
Background The testes are highly susceptible to the adverse effects of chemotherapy and radiation at all stages of life. Exposure to these threats mainly occurs during cancer treatment and as an occupational hazard in radiation centers. The present study investigated the regenerative ability of adipose-derived mesenchymal stem cells (ADMSCs) against the adverse effects of cisplatin on the structure and function of the testes. Methods New Zealand white rabbits (N = 15) were divided into three groups of five: a negative control group (no treatment), a cisplatin group (single dose of cisplatin into each testis followed three days later by a PBS injection), and a cisplatin + ADMSCs group (cisplatin injection followed three days later by an ADMSC injection). On day 45 post-treatment, serum testosterone levels were evaluated, and the testes and epididymis were collected for histology, oxidative stress examination, and epididymal sperm analysis. Results Cisplatin caused damage to the testicular tissue and decreased serum testosterone levels, epididymal sperm counts, and oxidants. An antioxidant imbalance was detected due to increasing malondialdehyde (MDA) and reduced glutathione (GSH) levels in testicular tissue. The ADMSC-treated group displayed a moderate epididymal sperm count, adequate antioxidant protection, suitable hormone levels, and enhanced testicular tissue morphology. Conclusions ADMSCs treatment repaired damaged testicular tissue, enhanced biochemical parameters, and modified pathological changes caused by cisplatin.
Infertility is a serious medical, economic, and psychological problem in the society. Male factor infertility, due to defective spermatogenesis as a result of a failure in germ cell proliferation and differentiation, appears to be the cause of 25–50% of infertility cases. According to several surveys, testicular degeneration can be caused by a variety of physical, chemical, and microbial causes. A stem cell is a non-specialized cell which is characterized by self-renewal by mitotic cell division and able to differentiate to specialized cells for the various tissues of the body. The data were obtained and analyzed from different databases (PubMed, Google Scholar, Egyptian Knowledge Bank, Elsevier, Medline, Embase, ProQuest, and BMC). This review discusses the causes, symptoms, and grades of testicular degeneration and the use of different types of stem cells in regeneration. And its conclusion based on previous researches and trials, MSCs are considered effective therapy for testicular degeneration.
The present study was investigated the anatomical features of the gastrointestinal tract in the Nile crocodile with detailed information about its arterial blood supply. Four adult Nile crocodiles were used for studying the morphology, histology of digestive tract and its arterial supply. The crocodile was euthanized then fixed in situ with 10% formalin to be dissected. Other fresh specimen was sectioned into small pieces for histological investigation. Two specimens were injected by colored latex neoprene through the heart for arterial study. The gastrointestinal tract composed of long straight esophagus, two sacs stomach, and double looped duodenum occupying pancreas, coiled small intestine and colorectum. The arterial blood supply originated from the celiacomesentric artery which gave up three branches; right gastric, intestinal and gastro duodenal arteries. The mucosal lining of the all digestive tract was simple columnar epithelium varied from secretory to absorptive, lamina propria was mostly fibroelastic connective tissue contains either glands or lymphocytes. Tunica musculosa frequently formed of inner circular and outer longitudinal smooth muscles excluding the fundic part of stomach had middle layer.
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