No abstract

Comparing the control and diabetic subjects a significant shift towards Th1 response in T1 diabetes mellitus for Hsp60 AA437-460 was observed.

an elimination-challenge procedure. The patient ful®lled all the diagnostic criteria of FIE (1, 5): vomiting and/or diarrhea occurring within 24 h of the challenge, stool containing blood and leukocytes, and a rise in PNL of .3500/mm 3 . We also observed a rise in the eosinophil count.Although the clinical picture in our patient seems to be clear, the mechanism remains obscure. As the target organ was the gastrointestinal tract, we think that the cow's milk antigens probably present in the amniotic¯uid might have been responsible.

A missing first phase and a decreased total C-peptide response during an IVGTT was characteristic for the A3243G mutation. The fasting C-peptide level of the carriers did not differ from the controls. Circulating ICA was present in some patients, but GAD, IA-2 and mitochondrial antibodies were absent. All subjects had HLA-DR1-DQ5 haplotype, and either -DQ5 or -DQ6 alleles.