Describir los resultados del tratamiento con braquiterapia ocular en ojos únicos en pacientes con retinoblastoma (Rb) bilateral, así como las complicaciones de su uso como tratamiento primario o secundario. Métodos: Serie de casos donde se identificaron todos los pacientes con Rb en el Hospital Infantil de México tratados con braquiterapia ocular con yodo-125 como salvamento ocular después del fallo en el control de la neoplasia mediante quimioterapia intravenosa, tratamiento focal con láser o crioterapia y radioterapia externa. Resultados: Se incluyeron un total de siete pacientes, dos pacientes eran del sexo femenino, y cinco, de sexo masculino. Dos pacientes tenían Rb hereditario y seis eran bilaterales. Tres de los ojos tratados con braquiterapia eran derechos. El seguimiento promedio de estos pacientes fue de 5.35 años (rango 3.3 a 11 años). El éxito del tratamiento se alcanzó en cinco de los siete pacientes. Dos pacientes fueron enucleados a pesar del tratamiento con braquiterapia por falla en el control de la neoplasia. Uno de los pacientes falleció por neoplasia secundaria. Conclusiones: El tratamiento con braquiterapia ocular en un hospital de tercer nivel ofrece posibilidades de preservación ocular en pacientes con Rb bilateral y tratamiento oncológico máximo.
Objective: To describe results and complications of salvage eye treatment with brachytherapy in patients with diagnosis of bilateral retinoblastoma (Rb) and only one eye. Methods: Case series where we included all retinoblastoma patients treated with ocular brachytherapy with Iodine-125 at the Hospital Infantil de Mexico after failure of eye salvage with intravenous chemotherapy, focal transpupillary laser o transconjunctival cryotherapy and external beam radiotherapy. Results: We analyzed 7 patients, 2 females and 5 males. Two had hereditary retinoblastoma and all had bilateral disease. Mean follow-up after treatment was 5.35 years (range 3.3-11 years). Tumor control was achieved in five of seven patients; two patients undergone enucleation due to failure to achieve tumor control. One of the patients died because of secondary neoplasm. Conclusions: Ocular brachytherapy treatment in a tertiary care center offers possibilities of ocular preservation in patients with bilateral Rb and maximum oncological treatment.
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