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Background Graves’ disease (GD) is an autoimmune thyroid condition that causes hyperthyroidism in children and adolescents through stimulation by thyroid receptor antibodies. Objective The aim of this study is to determine the characteristics of Graves’ disease in children and adolescents in Medina, the Kingdom of Saudi Arabia, with comparison to those seen in other countries. Methods This is a retrospective chart review of children and adolescents diagnosed with Graves’ disease between January 2010 and May 2021. Results Fifty-eight patients aged 12. 02 ± 4.85 years were identified, of which 44 (75.9%) were females. Exophthalmos (63.8%), neck swelling (60.3%), palpitation (46.6%), and tremors (29.3%) were the most common presenting manifestations. Vitiligo and alopecia were the only autoimmune diseases seen in our patients with (1.72%) each. One (1.72%) patient was treated with radioactive iodine, 54 (93.1%) received carbimazole, and 6 (10.3%) underwent thyroidectomy. Conclusion In our study we found that Graves’ disease is more common in females. Neck swelling, palpitation, and tremor were the main manifestations. Compared with other countries, there was a higher frequency of exophthalmos and lower frequencies of associated autoimmune conditions. The primary treatment was antithyroid medication, whereas thyroidectomy and radioiodine were used less frequently. Presentation: No date and time listed

Complete denture is still the most common way to treat edentulism. Therefore, achieving optimum retention and stability is an essential and dynamic issue to improve the quality of life. The aim of this study was to evaluate denture retention for one year follow up. Material and methods: 12 patients from the outpatient clinic of Prosthodontics Department (Faculty of Dentistry, Minia University, Egypt) were included in this study. They were selected out of sixty examined patients. The age ranges were 55-67 years. They have completely edentulous ridges and having Class III broad and rounded ridge with adequate height and width according to Cawood and Howell classification of edentulous mandibles. The protocol of the study was approved by the Local Research and Ethics Committee. Patients received complete maxillary and mandibular dentures following the conventional steps of complete denture construction. A force measurement gauge was used for measuring the retention for mandibular denture. The retention was recorded after two weeks from denture insertion, three, six and twelve months. Data was statistically analyzed using t test at a significance level<0.05. Results: The retention values for the mandibular dentures showed a statistically insignificant change with time along the follow period (p=0.065). Conclusion: The present results showed that the time cannot be considered as an effective factor for improvement of mandibular denture retention.