Butenolides and their analogues represent a wide range of natural compounds of a medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide, were isolated and showed biological activities. In this work we have studied the reactivity of some alkylidene butenolide and their antibacterial activity. the study is of a scientific interest in terms of the synthesis of new compounds (Butenolide 01: 5-hydroxy-5-(1-methoxypropan-2-yl)-4-methylfuran-2(5H)-one, Butenolide 02:5-(1-methoxypropan-2-yl)-4-methylfuran-2(5H)-one) that have not been studied before by other researchers; and of an economic importance because of its synthesis process which is easy and inexpensive. Moreover, butenolide showed a positive antimicrobial activity (antibiotic) against pathogenic bacteria (mainly Enterobacter hafniae).

Butenolides and their analogues represent a wide range of natural compounds of a medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide, were isolated and showed biological activities. In this work we have studied the reactivity of some alkylidene butenolide and their antibacterial activity. the study is of a scientific interest in terms of the synthesis of new compounds (Butenolide 01: 5-hydroxy-5-(1-methoxypropan-2-yl)-4-methylfuran-2(5H)-one, Butenolide 02: 5-(1-methoxypropan-2-yl)-4-methylfuran-2(5H)-one) that have not been studied before by other researchers; and of an economic importance because of its synthesis process which is easy and inexpensive. Moreover, butenolide showed a positive antimicrobial activity (antibiotic) against pathogenic bacteria (mainly Enterobacter hafniae).

Butenolides are a class of lactones with a four carbon heterocyclic ring structure.They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is sometimes referred to as simply "butenolide". A common biochemically important butenolide is ascorbic acid (vitamin C).The butenolide and their analogues represent a wide range of the natural compounds of medical and biological importance.In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide were isolated and showed biological activities.In this work we have studied the reactivity of some alkylidene butenolide and carried out their antibacterial activity.