Upon photoinduced CO release, all the Ru(ii) complexes acquired cytotoxicity against MCF-7 that may be attributed to the liberated CO and CO-depleted metal fragments including the liberated Coligands. Ru(ii) complex of the unsubstituted ligand exhibited the highest activity.
Tricarbonyl Re(i) complexes are piled in the intercellular junction and diffused inside the cells. This led to DNA fragmentations and both apoptotic and necrotic cell death.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.