Background: Epilepsy patients in developing countries is quite high. A person can have epilepsy within a certain time limit, but also not a few people who survive with this condition for life. This situation will affect cognitive function. Cognitive function impairment in epilepsy patients can be triggered by various factors related to aetiology, clinical, and others. Therefore, we tried to find the factors that influence the cognitive function in epilepsy patients.Methods: This study was an observational analytic study with a cross-sectional design. The study was conducted using primary data obtained from direct interviews and MMSE examination and secondary data obtained from medical records to confirm the diagnosis of epilepsy. Samples were collected based on the diagnosis of neurologist in the patient's medical record at the Regional General Hospital Dr. Zainoel Abidin Banda Aceh from October to December 2019. This study involved thirty-four epilepsy patients.Result: There were cognitive function decreased in recalling 47,1% and 26,5% in Attention and calculation. The relationship between the frequency of seizure (p = 0.028) and therapy (p = 0.012) on the  MMSE .Conclusion: Politherapy was the dominant factor affecting the MMSE score of epilepsy patients.

HEMICHOREA/HEMIBALLISM ASSOCIATED WITH NONKETOTIC HYPERGLYCEMIC ON ACUTE ISCHEMIC STROKEABSTRACTHemichorea/hemiballism (HCHB) associated with nonketotic hyperglycemia in acute ischemic stroke is a well-recognized syndrome characterized by the sudden occurrence of hemichorea or more severe expression like hemiballism. The hyperkinetic movements involve the face, arm, or leg. HCHB in acute ischemic stroke is a movement disorder that is rarely reported with hyperkinetic movement. This case report aimed to describe patient with HCHB associated with hyperglycemia as prior sign of stroke ischemic and propose a possible pathophysiology. We report three patients who had HCHB accompanied by hemiparesis, facial and hypoglossus nerve palsy. Laboratory results showed increased serum glucose levels and negative urine ketones. Imaging findings of head CT scan found an infarction in the basal ganglia. Patients are treated with antiplatelet and or anticoagulant therapy and correction of hyperglycemia with additional therapy of dopamine receptor antagonistThe combination of a recent or old striatal lesion and hyperglycemia induce HCHB, causing increased inhibition of the subthalamic nucleus and causing decreased GABAergic inhibition of the thalamus. Diabetes mellitus should always be suspected in patients who develop HCHB movements. When hyperglycemia is detected and treated, movement disorders resolve within a few days and the administration of dopamine receptor antagonists can be considered.Keywords: Hemiballism, hemichorea, hyperglycemia, ischemic strokeABSTRAKHemichorea/hemibalismus (HCHB) yang  berhubungan  dengan  hiperglikemia nonketotik pada stroke iskemik akut adalah sindrom yang ditandai oleh munculnya  hemichorea yang terjadi secara tiba-tiba atau disertai dengan gejala yang lebih berat, seperti   hemibalismus. Pergerakan hiperkinetik meliputi wajah, lengan dan tungkai. HCHB pada stroke iskemik akut merupakan gangguan pergerakan hiperkinetik yang jarang dilaporkan. Laporan kasus ini bertujuan untuk menggambarkan pasien yang mengalami keluhan HCHB sebagai gejala awal terjadinya stroke iskemik disertai dengan hiperglikemia dan memperkirakan  penjelasan patofisiologi yang mungkin terjadi pada pasien ini. Kami melaporkan tiga pasien dengan keluhan HCHB sebagai gejala awal stroke iskemik akut yang disertai hiperglikemia. Pada ketiga kasus tersebut keluhan disertai dengan paresis nervus fasialis, hipoglossus serta hemiparesis ekstremitas kontralateral lesi. Kadar glukosa serum meningkat dan keton urin negatif. Gambaran CT scan menunjukkan adanya infark di ganglia basalis. Pada tata laksana kami menemukan bahwa koreksi hiperglikemi disertai pemberian terapi antikoagulan dan atau antiplatelet serta agen neuroleptik dapat menyebabkan perbaikan luaran pada gejala HCHB secara perlahan. Kombinasi lesi striatal baru dan hiperglikemia dapat menginduksi terjadinya HCHB karena kedua hal tersebut dapat menyebabkan peningkatan inhibisi inti subtalamik dan gangguan  inhibisi GABAergic talamus. Diabetes melitus harus selalu dicurigai pada pasien dengan keluhan HCHB. Ketika hiperglikemia terdeteksi dan ditatalaksana, gangguan  gerakan menghilang dalam beberapa hari dan dapat dipertimbangkan dengan pemberian terapi neuroleptik.Kata kunci: Hemibalismus, hemichorea, hiperglikemia, stroke iskemik

The problem in this study is whether the learning outcomes and motivation biology class X SMA Jayaloka after applied learning model significantly Course Review Horay completely and increased? The method used in this study is quasi-experimental. The population is all students of class X SMA Jayaloka Academic Year 2016/2017. Sampling was carried out by random sampling study for every class has the ability and opportunity are relatively similar and was selected as a sample is a sample class as a class X.3. The data collection was done by using a test that consists of 13 essay questions. The collected data were analyzed using t-test. The result of study biology class X SMA Jayaloka after applied learning model significantly Course Review Horay completely. It can be seen from the average value of the pre-test of 52.88 increased to 86.21 in post-test. Whereas in the calculation of test-t obtained that t = 7.095. Furthermore t table compared with the value of a distribution list t with degrees of freedom df = n-1 = 34-1 = 33, α = 0.05 was obtained table = 2.045. Thus t (7.095)> t table (2.045). While the motivation class X SMA Jayaloka after applied learning models Course Review Horay increased from 54.96% to 99.96% were for.

Media scrapbook yang berbasis pemecahan masalah dapat meningkatakan kualitas pembelajaran, untuk meningkatkan perkambengan operasional kongkrit pada peserta didik. Penelitian pengembangan ini bertujuan untuk (1) Mengetahui tahapan dalam mengembangkan media scrapbook (2) Mengetahui kelayakan dari media scrapbook berbasis pemecahan masalah yang dilihat dari kevalidan media pembelajaran, kepraktisan media pembelajaran dan keefektifan media pembelajaran Media pembelajaran scrapbook dikembangkan menggunakan model ADDIE yaitu, analyze, design, development, implementation, dan evaluation. Subjek penelitian ini yaitu peserta didik kelas IV SDN Tegalrejo. Teknik pengumpulan data wawancara, observasi, angket. Instrumen penelitian yang digunakan yaitu lembar wawancara, lembar validasi, lembar observasi, lembar angket respon peserta didik. Analisis data, analisis validitas, analisis kepraktisan. Hasil penelitian pengembangan media scrapbook berbasis pemecahan masalah: (1) produk berupa media pembelajaran scrapbook yang dapat digunakan sebagai referensi sumber dan media untuk belajar. (2) hasil validasi yang dilakukan oleh ahli media mendapat presentase 94,16% dengan kriteria sangat valid, ahli materi mendapat presentase 89,58% dengan kreteria sangat valid, dan guru mendapatkan presentase 89,01% dengan kriteria sangat valid. Kemudian respon peserta didik secara terbatas mendapatkan presentase 80% dan pada uji lapangan mendapatkan presentase 80% dengan kriteris praktis. Sedangkan lembar keterlaksanaan mendapatkan rata-rata 99,15% dengan kriteria praktis.

A study of magnetic core resonance imaging modeling of biological tissue has been carried out in analyzing the effect of electrostatic forces with computational approach. This analysis aims to look at the effect of electric and magnetic force on the spectrum of breast cancer tissue. Physical parameters were determined using the modeled wave equation with the application of mathematical wolfram software 9. Computational or modeling results obtained 6 variations of the MRI spectrum showing the peak magnitude of the electric and magnetic spectrum changes by varying the resolution and distance. This is evidenced from the maximum resolution range ie the peak of the electric field spectrum at amplitude 25 a.u is at a concentration of 5 ppm. Resolution of spectrum peak medium is at concentration of 3-4 ppm whereas minimum resolution has 4 peak spectrum that is at concentration 1-2 ppm, 2-3ppm, 3-4ppm and 4ppm. the result of MRI spektrum for distance variation resulted in spectrum change, further reduced the distance then the mri spectrum in magnetic and electric field approaching spin 1.