In cryptocurrency, a block is a record of new transactions that could mean the location of cryptocurrency, medical data, or even voting records. Once each block is completed it's added to the chain, creating a chain of blocks: a blockchain. Because cryptocurrencies are encrypted, processing any transactions means solving complicated math problems using specified algorithm like SHA256 and Scrypt. People who solve these equations are rewarded with cryptocurrency in a process called mining. In this study the authors will find out the comparison of SHA256 and Scrypt to work on the blockchain. To find out the comparison between SHA256 and Scrypt some test will be done in this research. The test were given to both algorithm on some test System to observe which algorithm that has highest probability in finding new block. the results of the tests done in this paper show that Scrypt is much slower to hash than SHA256 but the Scrypt algorithm has greater chance to find a new block.