Background: Aim of this study was to assess the accuracy of transvaginal sonography (TVS) associated to Color or Power Doppler (CFD/PD) for the evaluation of size and spread of disease in cervical cancer as diagnostic tool in the preoperative evaluation. Method : All patients (pts) affected by cervical cancer were studied by TVS and CFD/PD. TVS probe was used also as a transrectal when deemed necessary. Tumor size was measured consecutively by gray scale sonography and using CFD/PD. Extension of the tumor to the parametria; to the corpus uteri, to the ovary, the bladder and the rectum was also evaluated. TVS findings were compared to gynecologic examination under anesthesia, MRI and laparoscopy and pathological specimen. Results: 20 cases were studied. 45% of pts had neoadjuvant chemotherapy. Tumor diameter measured by ultrasound correlated well with pathological specimen (r 0.82). Accuracy of the measurement was increased when tumor diameter was . 4 cm. TVS correctly diagnose the extension of disease to the bladder and to the corpus uteri in 90% of cases. Involvement of the parametria was supected by sonography in 45% of cases. Conclusions: TVS seems to be an accurate means of evaluation for tumor size and extension to adjacent organs, therefore TVS could be useful in the perioperative management of cervical cancer. F02Sonographic preoperative assessment of myometrial invasion in endometrial cancer C. Exacousto Á s, M. E. Romanini*, D. Rinaldo, C. Carusotti, D. Arduini, P. Benedetti-Panici* and C. Romanini Department of Obstet. and Gynecol., University of Tor Vergata, Rome, Italy; *Department of Gynecol., Campus Biomedico University, Rome, Italy Background: The purpose of this study was to assess the accuracy of transvaginal sonography (TVS) and Color/Power Doppler (CFD/PD) in evaluating the depth of myometrial invasion and preoperative staging of endometrial cancer. Method: All patients (pts) with histological confirmed endometrial cancer were evaluated sonographically before surgery. In all patients the endometrium was scanned by TVS to evaluate thickness, echogenicity, border, intraluminal fluid and intracavitary masses. CFD/PD were used to evaluate vessels distribution and resistance indices: Myometrial infiltration was evaluated more or less than 50%. Sonographic results were compared to histological staging obtained after surgery. Results: 53 patients were enrolled. All had endometrial thickness . 5 mm, mean thickness 19.5^10.5 mm. Myometrial invasion was , 50% in 35 pts, TVS evaluation was exact in 33 cases, with a sensitivity of 94% and a positive predictive value (PPV) of 94%. An infiltration . 50% was seen with TVS in 12 pts and was histologically confirmed in 11, with a sensitivity of 82% and PPV of 75%. Other 3 pts had a cervical infiltration, 3 had stage 3, one had stage 4. TVS evaluated correctly 48 patients with a sensitivity of 91%. Conclusions: TVS seems to be a valuable, noninvasive and unexpensive diagnostic method for the assessment of myometrial invasion. Background: The aim of this study w...