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An optimized digital filter for TV minimization in DBT imaging has been presented. The reliability of a logarithmic relation found between σB and λ values was confirmed and can be used in future work. Both quantitative and qualitative analyses performed in a clinical DBT image confirmed the relevance of this approach in improving image quality in DBT imaging. The results obtained are very encouraging about increasing SDNR in a short time and preserving the principal variations in image, the structures' boundary.

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The Clear-PEM scanner for positron emission mammography under development is described. The detector is based on pixelized LYSO crystals optically coupled to avalanche photodiodes and readout by a fast low-noise electronic system. A dedicated digital trigger (TGR) and data acquisition (DAQ) system is used for on-line selection of coincidence events with high efficiency, large bandwidth and small dead-time. A specialized gantry allows to perform exams of the breast and of the axilla. In this paper we present results of the measurement of detector modules that integrate the system under construction as well as the imaging performance estimated from Monte Carlo simulated data. r