Introduction: Xerostomia, commonly referred to as dry mouth syndrome, is a result of reduced or absent salivary flow producing mucosal dryness. Patient with xerostomia report symptoms such as mucosal dryness, burning sensation, oral discomforts, alterations in taste, and swallowing become more difficult, the lips are often dry with cracking, peeling, and atrophy. The use of drugs most often caused xerostomia. Several classes of used drugs can cause xerostomia, including antidepressants, anticholinergics, antispasmodics, antihistamines, antihypertensives, sedatives, diuretics, and dan bronchodilators. One of that drugs can causexerostomia is amlodipine as an antihypertensive drug, a class of Calcium channel blockers (CCBs). Objective: to report management of xerostomia caused by the use of amlodipine.Case: 55-year-old female patient came with complaints of dry mouth, thick saliva and difficult to swallow since five months ago. Patients went to the dentist in hospital then the dentist scaling her teeth but complaints have not improved.Patients returned to the dentist in hospital 2 months ago and then the patient was referred to the Rumah Sakit Gigi dan Mulut Universitas Airlangga. The patient had a history of hypertension and taking amlodipine 5 mg once daily since 2 years ago. Sialometry test showed foamy saliva that count 0.03 ml/min. Management: Given chlorine dioxide mouthwash, dry mouth gel, and chewing sugar free gum contain xilitol. Conclusion: management of xerostomia can be done with the use of chlorine dioxide mouthwash and dry mouth gel that can reduce dry mouth symptoms.

Latar belakang: Kandidiasis oral merupakan infeksi oportunistik yang sering ditemukan pada penderita yang terinfeksi human immunodeficiency virus (HIV) atau acquired immune deficiency syndrome (AIDS) ditandai dengan adanya penurunan jumlah CD4 + . Tujuan: Melaporkan kandidiasis oral pada pasien yang terinfeksi HIV/ AIDS. Kasus: Pasien wanita 40 tahun mengeluh langit-langit dan lidahnya terasa panas dan sakit sejak 3 bulan lalu. Gambaran klinis menunjukkan pseudomembran putih dapat dikerok, daerah sekitar kemerahan pada palatum kanan dan lidah, nodul multipel warna kemerahan pada palatum kanan dan kiri. Pemeriksaan jamur menunjukkan bentukan yeast dan pseudohifa. Pemeriksaan darah lengkap menunjukkan penurunan jumlah limfosit. Kandidiasis oral yang meluas ke orofaring disertai penurunan jumlah limfosit menimbulkan kecurigaan adanya infeksi HIV/AIDS sehingga dilakukan pemeriksaan CD4 + dan anti HIV. Hasil uji laboratorium menunjukkan jumlah CD4 + = 95 sel/mL, dan anti HIV reaktif. Pasien kemudian dirujuk ke Unit Perawatan Intermediate Penyakit Infeksi (UPIPI) RSUD Dr Soetomo untuk mendapatkan perawatan dengan anti retroviral (ARV). Kandidiasis oral dirawat menggunakan obat antijamur sistemik golongan azole. Simpulan: Kandidiasis oral yang telah diderita pada pasien dewasa muda dalam jangka waktu lama, sulit disembuhkan dan melibatkan daerah orofaring dapat menjadi penanda adanya infeksi HIV/AIDS.

Objective: to assess awareness of senior community in the Belawa distric, Wajo, South Sulawesi, Indonesia regarding their oral soft tissue abnormality specifically regard to Oral potentially malignant disorders, and to assess community ability to descript any pain or uncomfortably origin from their oral cavity. Methods: A self-made questionnaire written in Indonesia language was given to the old aged-adult based on WHO criteria with age range between 45 to 75 years old, who was willing to participate in this study. The questioner   consists some picture representing oral mucosal cavity with clinical feature of some ulcers, clinical feature of candida infection, and some clinical appearances of oral potentially malignant disorders. Results: In term of oral mucosal diseases questions, 22 (55%) participants had history of ulceration, however only 5 (45%) participants could specifically point out its previous ulcer location. However, history of pain only stated by 11 (28%) participants, 24 (60%) did not experienced any pain, and 5 (12%) did not answer the questions. Conclusion: knowledge and awareness regarding oral health lesion, especially the associated-potentially malignant lesion was far from ideal in the Belawa Community.

Plants are often used as herbal medicines because their active substances have known. Mangrove as herbal medicines are still under-researched; mangrove leafextract can be useful as anti-inflammatory, antibiotic, hemolytic drug, hypoglycemic has been specifically investigated for its inhibitory power againstStaphylococcus aureus as one of the causes of angular cheilitis and shows good results. This true experimental laboratory research with a posttest only control group design used 24 male white rats of the Wistar strain which were divided into group-1 were induced with S.aureus and given mangrove leaf extract, thegroup-2 was induced with S.aureus and given gentamicin, the group-3 was induced with C.albicans and given mangrove leaf extract, and the group-4 was induced with C.albicans and given miconazole. On the third day, wound length in the first group-1 was 0.23±0.2, in the group-2 was 0.00±0.0, in the group-3was 0.21±0.2, and the group-4 was 0.16±0.2. Based on the Friedman test, it showed significant results (p<0.05). It was concluded that mangrove leaf extract accelerated the wound closure process of angular cheilitis induced by S.aureus and C.albicans.