Pulmonary involvement is a rare event in the course of brucellosis, but the rate could be higher than currently estimated. In endemic regions, brucellosis should be considered as a causative agent in patients with pulmonary symptoms.
ÖzetAmaç: İnfeksiyon, doku hasarı, immünolojik tepkimeler ve inflamatuar süreç organizmada kısa sürede ortaya çıkan ve genel olarak akut faz yanıtı denen sistemik bir yanıta yol açar. Bu çalışmada akut brusellozlu hastalarda C-reaktif protein (CRP), ferritin ve fi brinojen gibi akut faz reaktanlarının düzeyinin saptanması amaçlanmıştır. Yöntemler: Bu çalışma, İnfeksiyon Hastalıkları ve Nöroloji Kliniklerinde, Nisan 2007 ve Ağustos 2008 tarihleri arasında izlenen 48 akut bruselloz olgusu (27 kadın, 21 erkek) ve 42 sağlıklı (22 kadın, 20 erkek) kişiden oluşan kontrol grubuyla yapılmıştır. Bulgular: Brusellozlu hastalarda albümin düzeyleri, kontrol grubuna göre istatistiksel olarak daha düşük (p<0.001), CRP ve ferritin düzeyleri ise daha yüksek bulunmuştur (p<0.001 ve p=0.03). Sonuçlar: Akut brusellozlu hastalarda serum CRP ve ferritin düzeyinin arttığı, albümin düzeyinin ise azaldığı tespit edilmiştir. Klimik Dergisi 2010; 23(2): 48-50.Anahtar Sözcükler: Bruselloz, akut faz reaktanları, C-reaktif protein, ferritin.
AbstractObjective: Infection, tissue damage, immunologic reactions and the infl ammatory process rapidly cause a systemic response in the organism, generally termed as acute phase response. The aim of this study was to evaluate the levels of acute phase reactants such as C-reactive protein (CRP), ferritin and fi brinogen in patients with acute brucellosis. Methods: This study was carried out in 48 patients (27 female, 21 male) with acute brucellosis who were followed at the Departments of Infectious Diseases and Neurology, between April 2007 and August 2008, and in 42 healthy controls (22 female, 20 male). Results: Serum albumin levels signifi cantly decreased (p<0.001), whereas CRP and ferritin levels signifi cantly increased (p<0.001 and p=0.03) in patients with acute brucellosis. Conclusions: It was concluded that serum levels of CRP and ferritin increased, while albumin decreased in patients with acute brucellosis. Klimik Dergisi 2010; 23(2): 48-50.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.