Amaç: Periodontal tedavi, kırık, restoratif uygulamalar, çürük gibi nedenlerle koruyucu tabakanın kalkması sonucu dentin tübülleri açığa çıkıp dişte hassasiyet oluşunca hassasiyet giderici ajanlardan yararlanılır. Çalışmamızın amacı; postoperatif diş hassasiyetini gidermek için kullanılan hassasiyet giderici ajanların, adeziv simantasyondaki bağlantıya etkisini incelemektir. Gereç ve SUMMARY Aim:The aim of the study is to research the effect that link is in adhesive cementation of dentin desensitizing agent, which use to desensitizate prosperative dental. Materials and Methods:In this study, sixteen intact human third molar teeth were used. The teeth were randomly divided into two different groups (n: 8). Two different dentin desensitizer agents, Gluma and Teethmate Desensitizer, are used in the study. All samples were embedded into PMMA-based acrylic resin. The occlusal enamel tissues of teeth were removed to expose occlusal dentin. In the first group, firstly Gluma Desensitizer was applied to dentin surfaces according to manufacturer' instruction. Gluma self-etch was applied to dentin surfaces