Drug information about Potentially Inappropriate Medications (PIMs) for elderly inpatients based on Beers 2019 is still limited in Indonesia. This study aimed to identify the incidence of PIMs using the 2019 Beers criteria in elderly patients and determine the factors associated with the incidence of PIMs. This research was observational with a cross-sectional approach. Data collection was carried out in the medical records section of a secondary referral hospital in Jakarta during August and September 2019. The number of samples was calculated using a sample size calculator, and data were obtained from the medical records of inpatients for the period January 2018-December 2018. The sampling of medical records was conducted with a non-probability sample with a purposive sampling technique. Inclusion criteria were medical records of inpatients aged 60 years or older. The exclusion criteria were patient medical records with incomplete data. The Beers 2019 criteria were used to identify PIMs. The results showed that from 325 medical records analyzed, PIMs were found in 122 (37.5%) elderly patients with a total incidence of 181 PIMs. Furosemide (25.4%) was the most common PIMs, followed by spironolactone (18.2%) and ranitidine (16%). The use of 10 medicines or more p<0.001, OR 4.26 95%CI (2.4-7.5) and a length of stay more than five days p=0.043 OR 1.65 95%CI (1.0- 2,6) was associated with a higher incidence of PIMs. However, age, gender, and the number of diagnoses were not significantly related to the incidence of PIMs. Health workers are advised to check serum creatinine in all hospitalized elderly patients and minimize the number of drugs used.
Adverse Drug Events (ADE) are closely related to Potentially Inappropriate Medications (PIMs) among the elderly, and can cause an increase in morbidity, mortality, and medical cost. The tools often used to assess PIMs include Beers and Screening Tool of Older Persons’ Prescriptions (STOPP) Criteria. Therefore, this study aimed to compare the PIMs identification using Beers 2019 and STOPP version 2 2016 Criteria. A descriptive-analytical method was used, and data were collected retrospectively from the medical records of 340 patients at Pondok Kopi Islamic Hospital period in 2018. The results showed that among 324 patients who met the inclusion criteria with Beers 2019, PIMs were present in 136 (41.85%), with 181 cases. Most of them were on criteria 3, namely 46 (25.41%) and 33 (18.23%) cases of furosemide and spironolactone, respectively. Meanwhile, out of 308 patients who met the inclusion criteria with STOPP, PIMs were found in 14 (4.55%) with a total of 18 cases. The use of aspirin or clopidogrel was observed in 7 people (38.89%) with uncontrolled severe hypertension, while NSAID usage was found in 3 uncontrolled severe hypertension patients (16.67%). Furthermore, there were 3 cases of aldosterone antagonist or ARB usage, which was combined with other drugs that can increase potassium without proper monitoring of the serum level (16.67%). In Pondok Kopi Islamic Hospital, Beers 2019 criteria can describe PIMs data better than the STOPP version 2 2016 due to data availability. Clinician and pharmacist collaboration is also needed in formulating the critical supporting data.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.