A large intrapericardial teratoma was found at necropsy in a 38-week stillborn fetus, in which prenatal diagnosis of hydrops fetalis and an echogenic cardiac mass had been made. Clinical and pathological data are reported. In utero intrapericardial teratomata lead to different outcomes depending on whether fetal hydrops is associated. When generalized fetal hydrops is not present, the outcome is good, even in cases with large pericardial effusions. When generalized fetal hydrops occurs, it often results in a poor outcome. In our literature review, we have found eight perinatal deaths in nine similar cases reported.
The nephrotic syndrome (NS) is reportedly as sociated with an increased risk of thromboembolic dis ease. We describe the case of an 8-year-old child with a steroid-responsive NS who developed a longitudinal si nus venous thrombosis. No family thrombophilic ten dency was found. To our knowledge, this is the second case published with these clinical characteristics. We sug gest that the sinus venous thrombosis was precipitated by the low levels of antithrombin III and hypoalbuminemia. Moreover, steroids probably played an etiological role. Key Words: Nephrotic syndrome—Sinus venous throm bosis—Venous thrombosis—Antithrombin III.
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