Pseudomonas species or pseudomonads are known for their metabolic and ubiquitous diversity which enables them to survive in extreme conditions such as in marine and terrestrial environments as well as in association with flora and fauna. The sequenced genomes of many strains of Pseudomonas spp. show their vast repertoire of biotechnological applicability potential with respect to their genetic makeup and also exhibit industrially important applications due to physicochemical tolerances to extreme conditions (such as temperature, pH, and toxic chemicals and solvents). The best studied species include opportunistic human and plant pathogens, soil bacteria, and the plant growth-promoting pseudomonads. Pseudomonas species also are plant-commensals known for exhibiting effective antimicrobial activities and enabling plants to retrieve key nutrients. Hence, studying Pseudomonas with respect to its various characteristics in response to plant interactions is a far more important subject to be studied for their effective applications. In this review, the Pseudomonads have been analyzed extensively for their genome; biomolecules produced and plant beneficial activities. Thus, the present work helps future endeavors for Pseudomonad research by streamlining the areas.

Background: The incidence of multiple pregnancy is increasing all over the world because of assisted reproductive technology or spontaneously as a result of numerous risk factors. The objective of this study was to study the perinatal outcome of multiple pregnancy in a tertiary care centre in central IndiaMethods: It is a prospective study total 2289 pregnant woman were enrolled. Out of which 72 pregnant women were either a twin or triplet. 2217 pregnant women were singleton and had acted as controls. Perinatal outcomes including perinatal morbidity and mortality in relation to history regarding any complication in the present pregnancy were noted and analyzed.Results: In case of multiple pregnancy 90.2% were conceived between 20-30 years of age and 9.8% more than 30 years.13.9% cases of multiple pregnancy were less than 34 weeks at the time of delivery. The IUGR in multifetal pregnant patient was significantly higher. Oligohydromnios was seen in 3 out of 72 multifetal gestation which accounted for 4.1%. The proportion of singleton and multiple pregnant females who had anemia during pregnancy was 92.33% and 91.67%. Most common indication of LSCS in multifetal gestation is abnormal presentation during labour accounting for 41.7% of LSCS. The most common indication for NICU admission in case of multifetal pregnancy was 80.8%.Conclusions: Majority of the twin pregnancy is high risk one, and as such all twin preganancies should have mandatory hospital delivery. Early diagnosis, antenatal, intra-natal and post-partum cares are necessary to improve the outcome.

Background: Abdominal hysterectomy is the most frequented way of hysterectomy in the world; today we have a lot of techniques for hysterectomy. Total Laparoscopic Hysterectomy (TLH) versus Total Abdominal Hysterectomy (TAH) needs experience an assessment of the learning curve. Objective of the study was to determine the feasibility and safety of TLH and TAH.Methods: Total 100 women were taken for study. Operating time, estimated blood loss, operating complication and length of stay in hospital were noted for each patient. The success rates of TLH were more compared to TAH. The operating time estimated blood loss, conversion to laparotomy was directly proportional to size of uterus.Results: There were no statistically significant differences between the two groups regarding age, body mass index (BMI), specimen weight, pre-operative hemoglobin (Hb) value and rates of the complications. The mean post-operative Hb value was significantly higher in group TLH than group TAH (11.3±0.7 gr/dl versus 10.6±1.6, p = 0.03). The mean time of operation was significantly longer in TLH than group TAH (105.4±22.9 minutes versus 74±18, p<0.001). The mean duration of hospital stay was statistically shorter in TLH compared to the TAH (2.47±0.5 days versus 4.86±1.1, p<0.001).Conclusions: Advantage of TLH over TAH are less blood loss, fewer wound infection and fever, smaller incisions, with less pain, shorter hospitalization time, speedier recovery.

Background:The objective of this study was to determine the outcomes of Low Molecular Weight Heparin Therapy (LMWH) given for various indications during pregnancy. Methods: In this context, a detailed retrospective analysis of all the patients who received LMWH for various indications over a period of two years from October 2015 to November 2017 at a single center, Sri Aurobindo Medical College and PG institute in Indore was performed. Results: Total 100 patients were studied, included over the period of 2 years for various indications for which Enoxaparin (1 mg/kg body weight OD/BD subcutaneously) was used. The indications were valvular heart disease with valve replacement and atrial fibrillation (54.0%), chronic deep vein thrombosis (DVT) (13.0%), thrombophilias (9.0%), recurrent pregnancy loses (21.0%) and prophylaxis for deep vein thrombosis (3.0%) in overall patients. Abortion was seen in 8.0 % patients; fetal growth restriction in 13% patients; and oligohydramnios, preeclampsia, gestational hypertension, placenta previa, abruptio placentae, postpartum hemorrhage patients and Stillbirth occurred in 4.0 % patients. No thromboembolic event was noted in any of the patients. None of the patients had any documented thrombocytopenia or clinical fracture. Conclusions: Low Molecular Weight Heparin Therapy (LMWH) used amongst pregnant women with various indications for anticoagulation therapy was associated with successful pregnancy outcome in the vast majority of cases. Further multicenter prospective studies and international registries of pregnant women on LMWH are necessary to broaden our knowledge in optimizing the care of women who require anticoagulation during pregnancy.research should help to clarify who should receive thromboprophylaxis, how to prevent adverse pregnancy outcomes in women with various thrombophilias, and how best to treat pregnant women who have a prosthetic heart valve. ACKNOWLEDGMENTSAuthors acknowledge to MRD department, SAIMS Indore for providing two-year data.

V. T. Rajshekar’s book ‘Caste – A Nation within the Nation’ (2007), which shifts his fundamental tone from protest to more serious analysis, is a turning point in his creative career. It explains how particular communities become marginalized within the confines of a nation-state. Even though casteism is implemented in all social institutions, caste is still a contentious subject in India, according to Rajshekar, who starts the book with this assertion. He makes the observation that in order to understand how deeply ingrained casteism is in India, one must look at the institution of marriage. He claims that the newspaper matrimonial pages are blatantly casteist and oppose caste integration, which should logically take place in a democracy. Rajshekar makes the point that knowledge of a country without knowledge of its castes and subcastes is essentially lacking. People, according to him, do not even realize that Indian society is made up of several castes and communities rather than being one cohesive community. Rajshekar claims that the caste system was created as a result of upper caste predominance, which led to rigorous social classification and, ultimately, a structure that may lead to war. He also demonstrates how the constitutional foundation can be used to address the marginalization of some communities within the framework of a nation-state. The book is a blatant allegory of the unethical power struggles in 20th-century India. In order to examine the viewpoint on discrimination of the lower strata of society, this research paper attempts to undertake a close study of Dr. Ambedkar’s work and its influence on literature. He also explains the marginalization of certain communities that happens within the framework of a Nation-state that can be solved by the constitutional base. The novel is a transparent allegory of the dirty power politics of the twentieth-century India. This research paper also tries to make a close reading of Dr. Ambedkar’s work and its impact on literature to assess the view on discrimination of the lower strata of society.