The pathogenetic role of hemostasis system disorders in the urogenital mycoplasmas infection (M. hominis, M. fermentans, M. genitalium and M. urealiticum) is studied. It is stated that the urogenital mycopeasmas a systemic lesion accompanied by infection is not a local process but chronic syndrome signs of disseminated intravascular blood coagulability. The increase of the indices of Villebrandts factor and 5-nucleotidase allows to judge of the functional state of vessels endothelium and infection activity.

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