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A bacterial species (Leuconostc oenos), well suited to acidic pH values, is proposed as substrate for the spectrophotometric determination of lysozyme activity. The principal advantage of this organism as the substrate is the ease of investigating lysozyme behavior at acidic p f f . Ihe sensitivity is lower rhan withMicrococcus luteus, but data are highly reproducible. 'This work was supported by contribution from Italian Ministry of Public Education (MPI 40%).

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