No abstract

Studies have shown that the use of herbal feed additives «Fitopank» by Grey Ukrainian cows 30 days before calving had a positive effect not only on the body of cows-mothers and the quality of their colostrum, but also on the physiological state of the born calves and the growth energy of young animals. Adding of «Fitopank» to the cows diet helped to improve the quality of colostrum and its immunological value. It showed a probable increase of total protein by 10-14 % (P < 0.05) and immunoglobulin level by 23-25 % (P < 0.01). The titratable acidity of both the first and second milk yields was 16 % lower (P < 0.01) than in the control group. The use of this feed additive improved the immunological status of newborn calves. In their blood there was an increase of total protein content by 17 % (P < 0.05), the level of gamma globulins by 18% (p < 0.05), IgG concentrations by 14 % (p < 0.05), Ig M by 13 % and Ig A by 17 % (p<0.05), as well as the growth of T-lymphocytes by 46% and B-lymphocytes by 24 % (p < 0.01), compared with control group. Detected increased growth of the 8-12 months bulls (by 2.3%, p < 0.05) of the experimental group may indicate their tendency for better development of meat qualities. Experiment showed that the absolute live weight increase of young animals up to 18 months was higher than the control by 10.9 kg (p < 0.05). The study of the herbal supplements efficacy for the prevention and treatment of animals immunodeficiency, as well as their impact on the metabolic processes and productive qualities of farm animals will be the focus of our further research.

Mycotoxins cause severe diseases in organisms of human and animals. They are difficult to diagnose, cause great economic damage. Sorbents are able to effectively bind and remove from the body through the digestive tract with a therapeutic or prophylactic purpose various endogenous and ekzogenous substances, microorganisms and they toxins, supermolecular structures and cells. The aim of the work is to study the effectiveness of use of Alfasorb for the neutralization of mixed fodders affected by mycotoxins and they impact on blood’s indexes and productive qualities of piglets of Large White Breed. Experience was conducted on 30 ty piglets. Animals of the control group received mixed feed that was produced in the conditions of the farm. The pigs of experimental group in addition to the basic diet received Alfasorb. We determined blood’s indexes for study the effect of feed additive Alfasorb on the physiological state of animals at 4 months of age. A morphological and histological study of liver was carried out. The analysis of the average daily weight gain of piglets showed that it was higher in period of growth in the animals of experimental group. In the animals of the experimental groups there was an increase in the number of red blood cells in comparison with the control. An unreliable decrease in blood serum levels which characterize the level of intermediate metabolism of proteins in the body (content of urea, creatinine and common bilirubin) was established in the animals of the experimental group as compared to the control group respectively by 22.83% ( td = 0.98, P ≤ 0.05), 7.12% (td = 1.92, P ≤ 0.05) and by 20.54% (td = 0.86, P ≤ 0.05). Most hepatocytes had large nucleus and intense color of the cytoplasm. This indicates the absence of alterative processes in the body. The results of the studies make it possible to assert that the inclusion the 0.2% Alfasorb to the compound of feed which contaminated with mycotoxins significantly reduces their negative effect on the piglets organism, has a positive effect on the growth rate, on the course of metabolic processes, also it promotes an increase in the liver of medium-sized hepatocyte nuclei, stimulates biosynthetic processes in that cells and ensures the formation of a full structure of histohematological barriers in the organism.